Shah S - Search Results

1

Glucocorticoid and cytokine crosstalk: Feedback, feedforward, and co-regulatory interactions determine repression or resistance.

Newton R, Shah S, Altonsy MO, Gerber AN. Newton R, et al. Among authors: shah s. J Biol Chem. 2017 Apr 28;292(17):7163-7172. doi: 10.1074/jbc.R117.777318. Epub 2017 Mar 10. J Biol Chem. 2017. PMID: 28283576 Free PMC article. Review.

2

Interplay between nuclear factor-κB, p38 MAPK, and glucocorticoid receptor signaling synergistically induces functional TLR2 in lung epithelial cells.

Bansal A, Mostafa MM, Kooi C, Sasse SK, Michi AN, Shah SV, Leigh R, Gerber AN, Newton R. Bansal A, et al. J Biol Chem. 2022 Apr;298(4):101747. doi: 10.1016/j.jbc.2022.101747. Epub 2022 Feb 19. J Biol Chem. 2022. PMID: 35189144 Free PMC article.

3

Roles for the mitogen-activated protein kinase (MAPK) phosphatase, DUSP1, in feedback control of inflammatory gene expression and repression by dexamethasone.

Shah S, King EM, Chandrasekhar A, Newton R. Shah S, et al. J Biol Chem. 2014 May 9;289(19):13667-79. doi: 10.1074/jbc.M113.540799. Epub 2014 Apr 1. J Biol Chem. 2014. PMID: 24692548 Free PMC article.

4

Negative Feed-forward Control of Tumor Necrosis Factor (TNF) by Tristetraprolin (ZFP36) Is Limited by the Mitogen-activated Protein Kinase Phosphatase, Dual-specificity Phosphatase 1 (DUSP1): IMPLICATIONS FOR REGULATION BY GLUCOCORTICOIDS.

Shah S, Mostafa MM, McWhae A, Traves SL, Newton R. Shah S, et al. J Biol Chem. 2016 Jan 1;291(1):110-25. doi: 10.1074/jbc.M115.697599. Epub 2015 Nov 6. J Biol Chem. 2016. PMID: 26546680 Free PMC article.

5

DUSP1 Maintains IRF1 and Leads to Increased Expression of IRF1-dependent Genes: A MECHANISM PROMOTING GLUCOCORTICOID INSENSITIVITY.

Shah S, King EM, Mostafa MM, Altonsy MO, Newton R. Shah S, et al. J Biol Chem. 2016 Oct 7;291(41):21802-21816. doi: 10.1074/jbc.M116.728964. Epub 2016 Aug 22. J Biol Chem. 2016. PMID: 27551049 Free PMC article.

6

Long-Acting β₂-Adrenoceptor Agonists Enhance Glucocorticoid Receptor (GR)-Mediated Transcription by Gene-Specific Mechanisms Rather Than Generic Effects via GR.

Rider CF, Altonsy MO, Mostafa MM, Shah SV, Sasse S, Manson ML, Yan D, Kärrman-Mårdh C, Miller-Larsson A, Gerber AN, Giembycz MA, Newton R. Rider CF, et al. Among authors: shah sv. Mol Pharmacol. 2018 Sep;94(3):1031-1046. doi: 10.1124/mol.118.112755. Epub 2018 Jun 29. Mol Pharmacol. 2018. PMID: 29959223 Free PMC article.

7

Cytokine-induced loss of glucocorticoid function: effect of kinase inhibitors, long-acting β(2)-adrenoceptor [corrected] agonist and glucocorticoid receptor ligands.

Rider CF, Shah S, Miller-Larsson A, Giembycz MA, Newton R. Rider CF, et al. Among authors: shah s. PLoS One. 2015 Jan 27;10(1):e0116773. doi: 10.1371/journal.pone.0116773. eCollection 2015. PLoS One. 2015. PMID: 25625944 Free PMC article.

8

Induction of regulator of G-protein signaling 2 expression by long-acting β2-adrenoceptor agonists and glucocorticoids in human airway epithelial cells.

Holden NS, George T, Rider CF, Chandrasekhar A, Shah S, Kaur M, Johnson M, Siderovski DP, Leigh R, Giembycz MA, Newton R. Holden NS, et al. Among authors: shah s. J Pharmacol Exp Ther. 2014 Jan;348(1):12-24. doi: 10.1124/jpet.113.204586. Epub 2013 Oct 25. J Pharmacol Exp Ther. 2014. PMID: 24163441

9

Glucocorticoid-driven transcriptomes in human airway epithelial cells: commonalities, differences and functional insight from cell lines and primary cells.

Mostafa MM, Rider CF, Shah S, Traves SL, Gordon PMK, Miller-Larsson A, Leigh R, Newton R. Mostafa MM, et al. Among authors: shah s. BMC Med Genomics. 2019 Jan 31;12(1):29. doi: 10.1186/s12920-018-0467-2. BMC Med Genomics. 2019. PMID: 30704470 Free PMC article.

10

An inhaled dose of budesonide induces genes involved in transcription and signaling in the human airways: enhancement of anti- and proinflammatory effector genes.

Leigh R, Mostafa MM, King EM, Rider CF, Shah S, Dumonceaux C, Traves SL, McWhae A, Kolisnik T, Kooi C, Slater DM, Kelly MM, Bieda M, Miller-Larsson A, Newton R. Leigh R, et al. Among authors: shah s. Pharmacol Res Perspect. 2016 Jul 12;4(4):e00243. doi: 10.1002/prp2.243. eCollection 2016 Aug. Pharmacol Res Perspect. 2016. PMID: 28116096 Free PMC article.

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