Hastie N - Search Results

1

Transcription factor Wilms' tumor 1 regulates developmental RNAs through 3' UTR interaction.

Bharathavikru R, Dudnakova T, Aitken S, Slight J, Artibani M, Hohenstein P, Tollervey D, Hastie N. Bharathavikru R, et al. Among authors: hastie n. Genes Dev. 2017 Feb 15;31(4):347-352. doi: 10.1101/gad.291500.116. Epub 2017 Mar 13. Genes Dev. 2017. PMID: 28289143 Free PMC article.

2

Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1.

Chau YY, Brownstein D, Mjoseng H, Lee WC, Buza-Vidas N, Nerlov C, Jacobsen SE, Perry P, Berry R, Thornburn A, Sexton D, Morton N, Hohenstein P, Freyer E, Samuel K, van't Hof R, Hastie N. Chau YY, et al. Among authors: hastie n. PLoS Genet. 2011 Dec;7(12):e1002404. doi: 10.1371/journal.pgen.1002404. Epub 2011 Dec 22. PLoS Genet. 2011. PMID: 22216009 Free PMC article.

3

Presence of WT1, the Wilm's tumor suppressor gene product, in nuclear poly(A)(+) ribonucleoprotein.

Ladomery MR, Slight J, Mc Ghee S, Hastie ND. Ladomery MR, et al. Among authors: hastie nd. J Biol Chem. 1999 Dec 17;274(51):36520-6. doi: 10.1074/jbc.274.51.36520. J Biol Chem. 1999. PMID: 10593950 Free article.

C., Calvo, C., Larsson, S. H., Lamond, A. I., and Hastie, N. D. (1998) Genes Dev. 12, 3217-3225) and binds to RNA in vitro (Caricasole, A., Duarte, A., Larsson, S. H., Hastie, N. D., Little, M., Holmes, G., Todorov, I., and Ward, A. (1996) Proc. Natl. …

C., Calvo, C., Larsson, S. H., Lamond, A. I., and Hastie, N. D. (1998) Genes Dev. 12, 3217-3225) and binds to RNA in vitro (Ca …

4

Expression in Xenopus oocytes shows that WT1 binds transcripts in vivo, with a central role for zinc finger one.

Ladomery M, Sommerville J, Woolner S, Slight J, Hastie N. Ladomery M, et al. Among authors: hastie n. J Cell Sci. 2003 Apr 15;116(Pt 8):1539-49. doi: 10.1242/jcs.00324. J Cell Sci. 2003. PMID: 12640038

5

Embryonic mesothelial-derived hepatic lineage of quiescent and heterogenous scar-orchestrating cells defined but suppressed by WT1.

Kendall TJ, Duff CM, Boulter L, Wilson DH, Freyer E, Aitken S, Forbes SJ, Iredale JP, Hastie ND. Kendall TJ, et al. Among authors: hastie nd. Nat Commun. 2019 Oct 15;10(1):4688. doi: 10.1038/s41467-019-12701-9. Nat Commun. 2019. PMID: 31615982 Free PMC article.

6

Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation.

Davies JA, Ladomery M, Hohenstein P, Michael L, Shafe A, Spraggon L, Hastie N. Davies JA, et al. Among authors: hastie n. Hum Mol Genet. 2004 Jan 15;13(2):235-46. doi: 10.1093/hmg/ddh015. Epub 2003 Nov 25. Hum Mol Genet. 2004. PMID: 14645201

7

Calcium/NFAT signalling promotes early nephrogenesis.

Burn SF, Webb A, Berry RL, Davies JA, Ferrer-Vaquer A, Hadjantonakis AK, Hastie ND, Hohenstein P. Burn SF, et al. Among authors: hastie nd. Dev Biol. 2011 Apr 15;352(2):288-98. doi: 10.1016/j.ydbio.2011.01.033. Epub 2011 Feb 3. Dev Biol. 2011. PMID: 21295565 Free PMC article.

8

WT1 expression in vessels varies with histopathological grade in tumour-bearing and control tissue from patients with breast cancer.

McGregor RJ, Chau YY, Kendall TJ, Artibani M, Hastie N, Hadoke PWF. McGregor RJ, et al. Among authors: hastie n. Br J Cancer. 2018 Dec;119(12):1508-1517. doi: 10.1038/s41416-018-0317-1. Epub 2018 Oct 30. Br J Cancer. 2018. PMID: 30374123 Free PMC article.

9

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes.

Davies RC, Calvio C, Bratt E, Larsson SH, Lamond AI, Hastie ND. Davies RC, et al. Among authors: hastie nd. Genes Dev. 1998 Oct 15;12(20):3217-25. doi: 10.1101/gad.12.20.3217. Genes Dev. 1998. PMID: 9784496 Free PMC article.

10

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source.

Chau YY, Bandiera R, Serrels A, Martínez-Estrada OM, Qing W, Lee M, Slight J, Thornburn A, Berry R, McHaffie S, Stimson RH, Walker BR, Chapuli RM, Schedl A, Hastie N. Chau YY, et al. Among authors: hastie n. Nat Cell Biol. 2014 Apr;16(4):367-75. doi: 10.1038/ncb2922. Epub 2014 Mar 9. Nat Cell Biol. 2014. PMID: 24609269 Free PMC article.

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