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The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago.
Murakami T, Kiyuna T, Kawaguchi K, Igarashi K, Singh AS, Hiroshima Y, Zhang Y, Zhao M, Miyake K, Nelson SD, Dry SM, Li Y, DeLong JC, Lwin TM, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. Murakami T, et al. Among authors: zhao m. Cell Cycle. 2017 Jun 3;16(11):1046-1052. doi: 10.1080/15384101.2017.1304340. Epub 2017 Mar 15. Cell Cycle. 2017. PMID: 28296559 Free PMC article.
Methods for the development of tumor-targeting bacteria.
Hoffman RM, Zhao M. Hoffman RM, et al. Among authors: zhao m. Expert Opin Drug Discov. 2014 Jul;9(7):741-50. doi: 10.1517/17460441.2014.916270. Expert Opin Drug Discov. 2014. PMID: 24949888 Review.
Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models.
Hiroshima Y, Zhang Y, Murakami T, Maawy A, Miwa S, Yamamoto M, Yano S, Sato S, Momiyama M, Mori R, Matsuyama R, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Zhao M, Hoffman RM. Hiroshima Y, et al. Among authors: zhao m. Oncotarget. 2014 Dec 15;5(23):12346-57. doi: 10.18632/oncotarget.2641. Oncotarget. 2014. PMID: 25402324 Free PMC article.
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