Taylor RE - Search Results

1

Synthesis and Biological Evaluation of 7-Deoxy-Epothilone Analogues.

Woods LM, Arico JW, Frein JD, Sackett DL, Taylor RE. Woods LM, et al. Among authors: taylor re. Int J Mol Sci. 2017 Mar 17;18(3):648. doi: 10.3390/ijms18030648. Int J Mol Sci. 2017. PMID: 28304361 Free PMC article.

2

Conformation-activity relationships in polyketide natural products: a new perspective on the rational design of epothilone analogues.

Taylor RE, Chen Y, Beatty A, Myles DC, Zhou Y. Taylor RE, et al. J Am Chem Soc. 2003 Jan 8;125(1):26-7. doi: 10.1021/ja028196l. J Am Chem Soc. 2003. PMID: 12515494

3

Conformation-activity relationships in polyketide natural products. Towards the biologically active conformation of epothilone.

Taylor RE, Chen Y, Galvin GM, Pabba PK. Taylor RE, et al. Org Biomol Chem. 2004 Jan 7;2(1):127-32. doi: 10.1039/b312213c. Epub 2003 Nov 20. Org Biomol Chem. 2004. PMID: 14737671

4

A unique mode of microtubule stabilization induced by peloruside A.

Huzil JT, Chik JK, Slysz GW, Freedman H, Tuszynski J, Taylor RE, Sackett DL, Schriemer DC. Huzil JT, et al. Among authors: taylor re. J Mol Biol. 2008 May 16;378(5):1016-30. doi: 10.1016/j.jmb.2008.03.026. Epub 2008 Mar 19. J Mol Biol. 2008. PMID: 18405918 Free PMC article.

5

Electrophile-induced ether transfer: stereoselective synthesis of 2,6-disubstituted-3,4-dihydropyrans.

Kartika R, Frein JD, Taylor RE. Kartika R, et al. Among authors: taylor re. J Org Chem. 2008 Jul 18;73(14):5592-4. doi: 10.1021/jo800704d. Epub 2008 Jun 21. J Org Chem. 2008. PMID: 18570473

6

New sources of chemical diversity inspired by biosynthesis: rational design of a potent epothilone analogue.

Frein JD, Taylor RE, Sackett DL. Frein JD, et al. Among authors: taylor re. Org Lett. 2009 Aug 6;11(15):3186-9. doi: 10.1021/ol900971r. Org Lett. 2009. PMID: 19572566 Free PMC article.

7

Application of stereoselective ether transfer to the synthesis of isotactic polyethers.

Liu K, Arico JW, Taylor RE. Liu K, et al. Among authors: taylor re. J Org Chem. 2010 Jun 18;75(12):3953-7. doi: 10.1021/jo100094d. J Org Chem. 2010. PMID: 20481506

8

Mutations in the β-tubulin binding site for peloruside A confer resistance by targeting a cleft significant in side chain binding.

Begaye A, Trostel S, Zhao Z, Taylor RE, Schriemer DC, Sackett DL. Begaye A, et al. Among authors: taylor re. Cell Cycle. 2011 Oct 1;10(19):3387-96. doi: 10.4161/cc.10.19.17706. Epub 2011 Oct 1. Cell Cycle. 2011. PMID: 21926482 Free PMC article.

9

The synthesis and biological evaluation of desepoxyisotedanolide and a comparison with desepoxytedanolide.

Naini A, Muthukumar Y, Raja A, Franke R, Harrier I, Smith AB 3rd, Lee D, Taylor RE, Sasse F, Kalesse M. Naini A, et al. Among authors: taylor re. Angew Chem Int Ed Engl. 2015 Jun 1;54(23):6935-9. doi: 10.1002/anie.201501526. Epub 2015 Apr 27. Angew Chem Int Ed Engl. 2015. PMID: 25914374

10

Conformation-guided analogue design identifies potential antimalarial compounds through inhibition of mitochondrial respiration.

Larsen EM, Chang CF, Sakata-Kato T, Arico JW, Lombardo VM, Wirth DF, Taylor RE. Larsen EM, et al. Among authors: taylor re. Org Biomol Chem. 2018 Aug 1;16(30):5403-5406. doi: 10.1039/c8ob01257a. Org Biomol Chem. 2018. PMID: 30009295 Free PMC article.

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