Zimmerman DM - Search Results

1

Synthesis and analgesic properties of N-substituted trans-4a-aryldecahydroisoquinolines.

Zimmerman DM, Cantrell BE, Swartzendruber JK, Jones ND, Mendelsohn LG, Leander JD, Nickander RC. Zimmerman DM, et al. J Med Chem. 1988 Mar;31(3):555-60. doi: 10.1021/jm00398a011. J Med Chem. 1988. PMID: 2831363

2

Discovery of a potent, peripherally selective trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine opioid antagonist for the treatment of gastrointestinal motility disorders.

Zimmerman DM, Gidda JS, Cantrell BE, Schoepp DD, Johnson BG, Leander JD. Zimmerman DM, et al. J Med Chem. 1994 Jul 22;37(15):2262-5. doi: 10.1021/jm00041a003. J Med Chem. 1994. PMID: 8057274

3

Structure-activity relationships of trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine antagonists for mu- and kappa-opioid receptors.

Zimmerman DM, Leander JD, Cantrell BE, Reel JK, Snoddy J, Mendelsohn LG, Johnson BG, Mitch CH. Zimmerman DM, et al. J Med Chem. 1993 Oct 1;36(20):2833-41. doi: 10.1021/jm00072a001. J Med Chem. 1993. PMID: 8410998

4

Synthesis of a series of aryl kainic acid analogs and evaluation in cells stably expressing the kainate receptor humGluR6.

Cantrell BE, Zimmerman DM, Monn JA, Kamboj RK, Hoo KH, Tizzano JP, Pullar IA, Farrell LN, Bleakman D. Cantrell BE, et al. Among authors: zimmerman dm. J Med Chem. 1996 Sep 13;39(19):3617-24. doi: 10.1021/jm960155a. J Med Chem. 1996. PMID: 8809152

5

Synthesis and evaluation of a series of novel 2-[(4-chlorophenoxy)methyl]benzimidazoles as selective neuropeptide Y Y1 receptor antagonists.

Zarrinmayeh H, Nunes AM, Ornstein PL, Zimmerman DM, Arnold MB, Schober DA, Gackenheimer SL, Bruns RF, Hipskind PA, Britton TC, Cantrell BE, Gehlert DR. Zarrinmayeh H, et al. Among authors: zimmerman dm. J Med Chem. 1998 Jul 16;41(15):2709-19. doi: 10.1021/jm9706630. J Med Chem. 1998. PMID: 9667962

6

Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists.

Zarrinmayeh H, Zimmerman DM, Cantrell BE, Schober DA, Bruns RF, Gackenheimer SL, Ornstein PL, Hipskind PA, Britton TC, Gehlert DR. Zarrinmayeh H, et al. Among authors: zimmerman dm. Bioorg Med Chem Lett. 1999 Mar 8;9(5):647-52. doi: 10.1016/s0960-894x(99)00082-7. Bioorg Med Chem Lett. 1999. PMID: 10201822

7

Selective opioid receptor agonists and antagonists: research tools and potential therapeutic agents.

Zimmerman DM, Leander JD. Zimmerman DM, et al. J Med Chem. 1990 Mar;33(3):895-902. doi: 10.1021/jm00165a002. J Med Chem. 1990. PMID: 2155322 Review. No abstract available.

8

Design and synthesis of a novel series of 1,2-disubstituted cyclopentanes as small, potent potentiators of 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic acid (AMPA) receptors.

Shepherd TA, Aikins JA, Bleakman D, Cantrell BE, Rearick JP, Simon RL, Smith EC, Stephenson GA, Zimmerman DM, Mandelzys A, Jarvie KR, Ho K, Deverill M, Kamboj RK. Shepherd TA, et al. Among authors: zimmerman dm. J Med Chem. 2002 May 9;45(10):2101-11. doi: 10.1021/jm0105474. J Med Chem. 2002. PMID: 11985477

9

Discovery of an opioid kappa receptor selective pure antagonist from a library of N-substituted 4beta-methyl-5-(3-hydroxyphenyl)morphans.

Thomas JB, Atkinson RN, Namdev N, Rothman RB, Gigstad KM, Fix SE, Mascarella SW, Burgess JP, Vinson NA, Xu H, Dersch CM, Cantrell BE, Zimmerman DM, Carroll FI. Thomas JB, et al. Among authors: zimmerman dm. J Med Chem. 2002 Aug 1;45(16):3524-30. doi: 10.1021/jm020084h. J Med Chem. 2002. PMID: 12139463

10

Identification of (3R)-7-hydroxy-N-((1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)- 3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl)-1,2,3,4-tetrahydro- 3-isoquinolinecarboxamide as a novel potent and selective opioid kappa receptor antagonist.

Thomas JB, Atkinson RN, Vinson NA, Catanzaro JL, Perretta CL, Fix SE, Mascarella SW, Rothman RB, Xu H, Dersch CM, Cantrell BE, Zimmerman DM, Carroll FI. Thomas JB, et al. Among authors: zimmerman dm. J Med Chem. 2003 Jul 3;46(14):3127-37. doi: 10.1021/jm030094y. J Med Chem. 2003. PMID: 12825951

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

89 results

Search Page

Filters