Lamb DJ - Search Results

1

Neutralization of both IL-1α/IL-1β plays a major role in suppressing combined cigarette smoke/virus-induced pulmonary inflammation in mice.

Bucher H, Mang S, Keck M, Przibilla M, Lamb DJ, Schiele F, Wittenbrink M, Fuchs K, Jung B, Erb KJ, Peter D. Bucher H, et al. Among authors: lamb dj. Pulm Pharmacol Ther. 2017 Jun;44:96-105. doi: 10.1016/j.pupt.2017.03.008. Epub 2017 Mar 15. Pulm Pharmacol Ther. 2017. PMID: 28315490 Free article.

2

Importance of the IL-1 Axis in Haemophilus influenzae-stimulated M₁ Macrophages Driving Transepithelial Signaling.

Mang S, Braun A, Pairet N, Lamb DJ. Mang S, et al. Among authors: lamb dj. Am J Respir Cell Mol Biol. 2018 Mar;58(3):412-415. doi: 10.1165/rcmb.2017-0283LE. Am J Respir Cell Mol Biol. 2018. PMID: 29493324 No abstract available.

3

TRPV4 inhibition attenuates stretch-induced inflammatory cellular responses and lung barrier dysfunction during mechanical ventilation.

Pairet N, Mang S, Fois G, Keck M, Kühnbach M, Gindele J, Frick M, Dietl P, Lamb DJ. Pairet N, et al. Among authors: lamb dj. PLoS One. 2018 Apr 17;13(4):e0196055. doi: 10.1371/journal.pone.0196055. eCollection 2018. PLoS One. 2018. PMID: 29664963 Free PMC article.

4

Spleen tyrosine kinase inhibition blocks airway constriction and protects from Th2-induced airway inflammation and remodeling.

Tabeling C, Herbert J, Hocke AC, Lamb DJ, Wollin SL, Erb KJ, Boiarina E, Movassagh H, Scheffel J, Doehn JM, Hippenstiel S, Maurer M, Gounni AS, Kuebler WM, Suttorp N, Witzenrath M. Tabeling C, et al. Among authors: lamb dj. Allergy. 2017 Jul;72(7):1061-1072. doi: 10.1111/all.13101. Epub 2017 Jan 12. Allergy. 2017. PMID: 27906453

5

BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells.

Lamb DJ, Wollin SL, Schnapp A, Bischoff D, Erb KJ, Bouyssou T, Guilliard B, Strasser C, Wex E, Blum S, Thaler E, Nickel H, Radmacher O, Haas H, Swantek JL, Souza D, Canfield M, White D, Panzenbeck M, Kashem MA, Sanville-Ross M, Kono T, Sewald K, Braun A, Obernolte H, Danov O, Schaenzle G, Rast G, Maier GM, Hoffmann M. Lamb DJ, et al. J Pharmacol Exp Ther. 2016 Jun;357(3):554-61. doi: 10.1124/jpet.116.233155. Epub 2016 Apr 5. J Pharmacol Exp Ther. 2016. PMID: 27048659

6

Opposing effects of in vitro differentiated macrophages sub-type on epithelial wound healing.

Gindele JA, Mang S, Pairet N, Christ I, Gantner F, Schymeinsky J, Lamb DJ. Gindele JA, et al. Among authors: lamb dj. PLoS One. 2017 Sep 1;12(9):e0184386. doi: 10.1371/journal.pone.0184386. eCollection 2017. PLoS One. 2017. PMID: 28863189 Free PMC article.

7

Differential modulation of transendothelial electrical resistance by TRPV4 agonists is mediated by apoptosis and/or necrosis.

Pairet N, Mang S, Kiechle T, Laufhäger N, Dietl P, Lamb DJ. Pairet N, et al. Among authors: lamb dj. Biochem Biophys Rep. 2019 Sep 19;20:100672. doi: 10.1016/j.bbrep.2019.100672. eCollection 2019 Dec. Biochem Biophys Rep. 2019. PMID: 31650038 Free PMC article.

8

An EZH2-dependent transcriptional complex promotes aberrant epithelial remodelling after injury.

Le HQ, Hill MA, Kollak I, Keck M, Schroeder V, Wirth J, Skronska-Wasek W, Schruf E, Strobel B, Stahl H, Herrmann FE, Campos AR, Li J, Quast K, Knebel D, Viollet C, Thomas MJ, Lamb D, Garnett JP. Le HQ, et al. EMBO Rep. 2021 Aug 4;22(8):e52785. doi: 10.15252/embr.202152785. Epub 2021 Jul 5. EMBO Rep. 2021. PMID: 34224201 Free PMC article.

9

RORγt inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma.

Lamb D, De Sousa D, Quast K, Fundel-Clemens K, Erjefält JS, Sandén C, Hoffmann HJ, Kästle M, Schmid R, Menden K, Delic D. Lamb D, et al. Respir Res. 2021 May 22;22(1):158. doi: 10.1186/s12931-021-01743-7. Respir Res. 2021. PMID: 34022896 Free PMC article.

10

FKBP51 modulates steroid sensitivity and NFκB signalling: A novel anti-inflammatory drug target.

Kästle M, Kistler B, Lamla T, Bretschneider T, Lamb D, Nicklin P, Wyatt D. Kästle M, et al. Eur J Immunol. 2018 Nov;48(11):1904-1914. doi: 10.1002/eji.201847699. Epub 2018 Sep 14. Eur J Immunol. 2018. PMID: 30169894 Free PMC article.

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