Imredy JP - Search Results

1

Cardiac drug-drug interaction between HCV-NS5B pronucleotide inhibitors and amiodarone is determined by their specific diastereochemistry.

Lagrutta A, Regan CP, Zeng H, Imredy JP, Koeplinger K, Morissette P, Liu L, Wollenberg G, Brynczka C, Lebrón J, DeGeorge J, Sannajust F. Lagrutta A, et al. Among authors: imredy jp. Sci Rep. 2017 Mar 22;7:44820. doi: 10.1038/srep44820. Sci Rep. 2017. PMID: 28327633 Free PMC article.

2

Interaction between amiodarone and hepatitis-C virus nucleotide inhibitors in human induced pluripotent stem cell-derived cardiomyocytes and HEK-293 Cav1.2 over-expressing cells.

Lagrutta A, Zeng H, Imredy J, Balasubramanian B, Dech S, Lis E, Wang J, Zhai J, DeGeorge J, Sannajust F. Lagrutta A, et al. Toxicol Appl Pharmacol. 2016 Oct 1;308:66-76. doi: 10.1016/j.taap.2016.08.006. Epub 2016 Aug 9. Toxicol Appl Pharmacol. 2016. PMID: 27520758

3

Combining an in silico proarrhythmic risk assay with a tPKPD model to predict QTc interval prolongation in the anesthetized guinea pig assay.

Morissette P, Polak S, Chain A, Zhai J, Imredy JP, Wildey MJ, Travis J, Fitzgerald K, Fanelli P, Passini E, Rodriguez B, Sannajust F, Regan C. Morissette P, et al. Among authors: imredy jp. Toxicol Appl Pharmacol. 2020 Mar 1;390:114883. doi: 10.1016/j.taap.2020.114883. Epub 2020 Jan 23. Toxicol Appl Pharmacol. 2020. PMID: 31981640 Free PMC article.

4

[No title available]

[No authors listed] [No authors listed] PMID: 31962998

5

The anesthetized guinea pig: an effective early cardiovascular derisking and lead optimization model.

Morissette P, Nishida M, Trepakova E, Imredy J, Lagrutta A, Chaves A, Hoagland K, Hoe CM, Zrada MM, Travis JJ, Zingaro GJ, Gerenser P, Friedrichs G, Salata JJ. Morissette P, et al. J Pharmacol Toxicol Methods. 2013 Jul-Aug;68(1):137-49. doi: 10.1016/j.vascn.2013.04.010. Epub 2013 May 4. J Pharmacol Toxicol Methods. 2013. PMID: 23649000

6

Optimization of Ca(v)1.2 screening with an automated planar patch clamp platform.

Balasubramanian B, Imredy JP, Kim D, Penniman J, Lagrutta A, Salata JJ. Balasubramanian B, et al. Among authors: imredy jp. J Pharmacol Toxicol Methods. 2009 Mar-Apr;59(2):62-72. doi: 10.1016/j.vascn.2009.02.002. J Pharmacol Toxicol Methods. 2009. PMID: 19367686

7

Can Galactose Be Converted to Glucose in HepG2 Cells? Improving the in Vitro Mitochondrial Toxicity Assay for the Assessment of Drug Induced Liver Injury.

Xu Q, Liu L, Vu H, Kuhls M, Aslamkhan AG, Liaw A, Yu Y, Kaczor A, Ruth M, Wei C, Imredy J, Lebron J, Pearson K, Gonzalez R, Mitra K, Sistare FD. Xu Q, et al. Chem Res Toxicol. 2019 Aug 19;32(8):1528-1544. doi: 10.1021/acs.chemrestox.9b00033. Epub 2019 Jul 18. Chem Res Toxicol. 2019. PMID: 31271030

8

Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.

Kramer J, Himmel HM, Lindqvist A, Stoelzle-Feix S, Chaudhary KW, Li D, Bohme GA, Bridgland-Taylor M, Hebeisen S, Fan J, Renganathan M, Imredy J, Humphries ESA, Brinkwirth N, Strassmaier T, Ohtsuki A, Danker T, Vanoye C, Polonchuk L, Fermini B, Pierson JB, Gintant G. Kramer J, et al. Sci Rep. 2020 Mar 27;10(1):5627. doi: 10.1038/s41598-020-62344-w. Sci Rep. 2020. PMID: 32221320 Free PMC article.

9

Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.

Kramer J, Himmel HM, Lindqvist A, Stoelzle-Feix S, Chaudhary KW, Li D, Bohme GA, Bridgland-Taylor M, Hebeisen S, Fan J, Renganathan M, Imredy J, Humphries ESA, Brinkwirth N, Strassmaier T, Ohtsuki A, Danker T, Vanoye C, Polonchuk L, Fermini B, Pierson JB, Gintant G. Kramer J, et al. Sci Rep. 2020 Jul 14;10(1):11884. doi: 10.1038/s41598-020-68819-0. Sci Rep. 2020. PMID: 32665705 Free PMC article.

10

Assessing use-dependent inhibition of the cardiac Na(+/-) current (I(Na)) in the PatchXpress automated patch clamp.

Penniman JR, Kim DC, Salata JJ, Imredy JP. Penniman JR, et al. Among authors: imredy jp. J Pharmacol Toxicol Methods. 2010 Sep-Oct;62(2):107-18. doi: 10.1016/j.vascn.2010.06.007. Epub 2010 Jun 22. J Pharmacol Toxicol Methods. 2010. PMID: 20601018

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