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Resveratrol Improves Vascular Function and Mitochondrial Number but Not Glucose Metabolism in Older Adults.
Pollack RM, Barzilai N, Anghel V, Kulkarni AS, Golden A, O'Broin P, Sinclair DA, Bonkowski MS, Coleville AJ, Powell D, Kim S, Moaddel R, Stein D, Zhang K, Hawkins M, Crandall JP. Pollack RM, et al. Among authors: moaddel r. J Gerontol A Biol Sci Med Sci. 2017 Nov 9;72(12):1703-1709. doi: 10.1093/gerona/glx041. J Gerontol A Biol Sci Med Sci. 2017. PMID: 28329397 Free PMC article. Clinical Trial.
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.
Price NL, Gomes AP, Ling AJ, Duarte FV, Martin-Montalvo A, North BJ, Agarwal B, Ye L, Ramadori G, Teodoro JS, Hubbard BP, Varela AT, Davis JG, Varamini B, Hafner A, Moaddel R, Rolo AP, Coppari R, Palmeira CM, de Cabo R, Baur JA, Sinclair DA. Price NL, et al. Among authors: moaddel r. Cell Metab. 2012 May 2;15(5):675-90. doi: 10.1016/j.cmet.2012.04.003. Cell Metab. 2012. PMID: 22560220 Free PMC article.
Targeted Metabolomics Shows Low Plasma Lysophosphatidylcholine 18:2 Predicts Greater Decline of Gait Speed in Older Adults: The Baltimore Longitudinal Study of Aging.
Gonzalez-Freire M, Moaddel R, Sun K, Fabbri E, Zhang P, Khadeer M, Salem N Jr, Ferrucci L, Semba RD. Gonzalez-Freire M, et al. Among authors: moaddel r. J Gerontol A Biol Sci Med Sci. 2019 Jan 1;74(1):62-67. doi: 10.1093/gerona/gly100. J Gerontol A Biol Sci Med Sci. 2019. PMID: 29788121 Free PMC article.
Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.
Semba RD, Zhang P, Zhu M, Fabbri E, Gonzalez-Freire M, Carlson OD, Moaddel R, Tanaka T, Egan JM, Ferrucci L. Semba RD, et al. Among authors: moaddel r. J Gerontol A Biol Sci Med Sci. 2019 Jan 1;74(1):129-136. doi: 10.1093/gerona/gly255. J Gerontol A Biol Sci Med Sci. 2019. PMID: 30380014 Free PMC article.
Targeted Deletion of Interleukin-6 in a Mouse Model of Chronic Inflammation Demonstrates Opposing Roles in Aging: Benefit and Harm.
Ma L, Nidadavolu LS, Yang H, Langdon J, Westbrook R, Tsui BMW, Lee TS, Hinson J, Ling S, Marx-Rattner R, Wu Y, Nguyen T, Tan J, Khadeer M, Moaddel R, Le A, Walston JD, Abadir PM. Ma L, et al. Among authors: moaddel r. J Gerontol A Biol Sci Med Sci. 2021 Jan 18;76(2):211-215. doi: 10.1093/gerona/glaa156. J Gerontol A Biol Sci Med Sci. 2021. PMID: 32585682 Free PMC article.
Serum Concentrations of Losartan Metabolites Correlate With Improved Physical Function in a Pilot Study of Prefrail Older Adults.
Lee JL, Zhang C, Westbrook R, Gabrawy MM, Nidadavolu L, Yang H, Marx R, Wu Y, Anders NM, Ma L, Bichara MD, Kwak MJ, Buta B, Khadeer M, Yenokyan G, Tian J, Xue QL, Siragy HM, Carey RM, de Cabo R, Ferrucci L, Moaddel R, Rudek MA, Le A, Walston JD, Abadir PM. Lee JL, et al. Among authors: moaddel r. J Gerontol A Biol Sci Med Sci. 2022 Dec 29;77(12):2356-2366. doi: 10.1093/gerona/glac102. J Gerontol A Biol Sci Med Sci. 2022. PMID: 35511890 Free PMC article. Clinical Trial.
Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet.
Jimenez-Gomez Y, Mattison JA, Pearson KJ, Martin-Montalvo A, Palacios HH, Sossong AM, Ward TM, Younts CM, Lewis K, Allard JS, Longo DL, Belman JP, Malagon MM, Navas P, Sanghvi M, Moaddel R, Tilmont EM, Herbert RL, Morrell CH, Egan JM, Baur JA, Ferrucci L, Bogan JS, Bernier M, de Cabo R. Jimenez-Gomez Y, et al. Among authors: moaddel r. Cell Metab. 2013 Oct 1;18(4):533-45. doi: 10.1016/j.cmet.2013.09.004. Cell Metab. 2013. PMID: 24093677 Free PMC article.
224 results