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LACTB is a tumour suppressor that modulates lipid metabolism and cell state.
Keckesova Z, Donaher JL, De Cock J, Freinkman E, Lingrell S, Bachovchin DA, Bierie B, Tischler V, Noske A, Okondo MC, Reinhardt F, Thiru P, Golub TR, Vance JE, Weinberg RA. Keckesova Z, et al. Among authors: lingrell s. Nature. 2017 Mar 30;543(7647):681-686. doi: 10.1038/nature21408. Epub 2017 Mar 22. Nature. 2017. PMID: 28329758 Free PMC article.
PISD is a mitochondrial disease gene causing skeletal dysplasia, cataracts, and white matter changes.
Zhao T, Goedhart CM, Sam PN, Sabouny R, Lingrell S, Cornish AJ, Lamont RE, Bernier FP, Sinasac D, Parboosingh JS; Care4Rare Canada Consortium; Vance JE, Claypool SM, Innes AM, Shutt TE. Zhao T, et al. Among authors: lingrell s. Life Sci Alliance. 2019 Mar 11;2(2):e201900353. doi: 10.26508/lsa.201900353. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30858161 Free PMC article.
Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity.
Jacobs RL, Zhao Y, Koonen DP, Sletten T, Su B, Lingrell S, Cao G, Peake DA, Kuo MS, Proctor SD, Kennedy BP, Dyck JR, Vance DE. Jacobs RL, et al. Among authors: lingrell s. J Biol Chem. 2010 Jul 16;285(29):22403-13. doi: 10.1074/jbc.M110.108514. Epub 2010 May 7. J Biol Chem. 2010. PMID: 20452975 Free PMC article.
Pioglitazone attenuates hepatic inflammation and fibrosis in phosphatidylethanolamine N-methyltransferase-deficient mice.
van der Veen JN, Lingrell S, Gao X, Quiroga AD, Takawale A, Armstrong EA, Yager JY, Kassiri Z, Lehner R, Vance DE, Jacobs RL. van der Veen JN, et al. Among authors: lingrell s. Am J Physiol Gastrointest Liver Physiol. 2016 Apr 1;310(7):G526-38. doi: 10.1152/ajpgi.00243.2015. Epub 2016 Jan 21. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 26797396 Free article.
22 results