Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion.
Leclerc I, Woltersdorf WW, da Silva Xavier G, Rowe RL, Cross SE, Korbutt GS, Rajotte RV, Smith R, Rutter GA.
Leclerc I, et al. Among authors: rutter ga.
Am J Physiol Endocrinol Metab. 2004 Jun;286(6):E1023-31. doi: 10.1152/ajpendo.00532.2003. Epub 2004 Feb 10.
Am J Physiol Endocrinol Metab. 2004.
PMID: 14871885
Free article.
We have recently shown that forced increases in AMPK activity inhibit insulin secretion from MIN6 cells (da Silva Xavier G, Leclerc I, Varadi A, Tsuboi T, Moule SK, and Rutter GA. Biochem J 371: 761-774, 2003). Here, we explore whether 1) glucose, metformin, or lept …
We have recently shown that forced increases in AMPK activity inhibit insulin secretion from MIN6 cells (da Silva Xavier G, Leclerc I, Varad …