Uchida S - Search Results

1

Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to high potassium intake.

Shoda W, Nomura N, Ando F, Mori Y, Mori T, Sohara E, Rai T, Uchida S. Shoda W, et al. Among authors: uchida s. Kidney Int. 2017 Feb;91(2):402-411. doi: 10.1016/j.kint.2016.09.001. Epub 2016 Oct 27. Kidney Int. 2017. PMID: 28341239 Free article.

2

Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone.

Chiga M, Rai T, Yang SS, Ohta A, Takizawa T, Sasaki S, Uchida S. Chiga M, et al. Among authors: uchida s. Kidney Int. 2008 Dec;74(11):1403-9. doi: 10.1038/ki.2008.451. Epub 2008 Sep 17. Kidney Int. 2008. PMID: 18800028 Free article.

3

Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure.

Ohta A, Rai T, Yui N, Chiga M, Yang SS, Lin SH, Sohara E, Sasaki S, Uchida S. Ohta A, et al. Among authors: uchida s. Hum Mol Genet. 2009 Oct 15;18(20):3978-86. doi: 10.1093/hmg/ddp344. Epub 2009 Jul 24. Hum Mol Genet. 2009. PMID: 19633012

4

Phosphatidylinositol 3-kinase/Akt signaling pathway activates the WNK-OSR1/SPAK-NCC phosphorylation cascade in hyperinsulinemic db/db mice.

Nishida H, Sohara E, Nomura N, Chiga M, Alessi DR, Rai T, Sasaki S, Uchida S. Nishida H, et al. Among authors: uchida s. Hypertension. 2012 Oct;60(4):981-90. doi: 10.1161/HYPERTENSIONAHA.112.201509. Epub 2012 Sep 4. Hypertension. 2012. PMID: 22949526 Free PMC article.

5

Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy.

Mori T, Kikuchi E, Watanabe Y, Fujii S, Ishigami-Yuasa M, Kagechika H, Sohara E, Rai T, Sasaki S, Uchida S. Mori T, et al. Among authors: uchida s. Biochem J. 2013 Nov 1;455(3):339-45. doi: 10.1042/BJ20130597. Biochem J. 2013. PMID: 23981180

6

WNK4 is the major WNK positively regulating NCC in the mouse kidney.

Takahashi D, Mori T, Nomura N, Khan MZ, Araki Y, Zeniya M, Sohara E, Rai T, Sasaki S, Uchida S. Takahashi D, et al. Among authors: uchida s. Biosci Rep. 2014 May 9;34(3):e00107. doi: 10.1042/BSR20140047. Biosci Rep. 2014. PMID: 24655003 Free PMC article.

7

Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters.

Kikuchi E, Mori T, Zeniya M, Isobe K, Ishigami-Yuasa M, Fujii S, Kagechika H, Ishihara T, Mizushima T, Sasaki S, Sohara E, Rai T, Uchida S. Kikuchi E, et al. Among authors: uchida s. J Am Soc Nephrol. 2015 Jul;26(7):1525-36. doi: 10.1681/ASN.2014060560. Epub 2014 Nov 5. J Am Soc Nephrol. 2015. PMID: 25377078 Free PMC article.

8

Kelch-Like Protein 2 Mediates Angiotensin II-With No Lysine 3 Signaling in the Regulation of Vascular Tonus.

Zeniya M, Morimoto N, Takahashi D, Mori Y, Mori T, Ando F, Araki Y, Yoshizaki Y, Inoue Y, Isobe K, Nomura N, Oi K, Nishida H, Sasaki S, Sohara E, Rai T, Uchida S. Zeniya M, et al. Among authors: uchida s. J Am Soc Nephrol. 2015 Sep;26(9):2129-38. doi: 10.1681/ASN.2014070639. Epub 2015 Jan 2. J Am Soc Nephrol. 2015. PMID: 25556166 Free PMC article.

9

Impaired degradation of medullary WNK4 in the kidneys of KLHL2 knockout mice.

Kasagi Y, Takahashi D, Aida T, Nishida H, Nomura N, Zeniya M, Mori T, Sasaki E, Ando F, Rai T, Uchida S, Sohara E. Kasagi Y, et al. Among authors: uchida s. Biochem Biophys Res Commun. 2017 May 27;487(2):368-374. doi: 10.1016/j.bbrc.2017.04.068. Epub 2017 Apr 14. Biochem Biophys Res Commun. 2017. PMID: 28414128

10

Role of ClC-K and barttin in low potassium-induced sodium chloride cotransporter activation and hypertension in mouse kidney.

Nomura N, Shoda W, Wang Y, Mandai S, Furusho T, Takahashi D, Zeniya M, Sohara E, Rai T, Uchida S. Nomura N, et al. Among authors: uchida s. Biosci Rep. 2018 Jan 30;38(1):BSR20171243. doi: 10.1042/BSR20171243. Print 2018 Feb 28. Biosci Rep. 2018. PMID: 29326302 Free PMC article.

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