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Page 1
Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function.
Leisegang MS, Fork C, Josipovic I, Richter FM, Preussner J, Hu J, Miller MJ, Epah J, Hofmann P, Günther S, Moll F, Valasarajan C, Heidler J, Ponomareva Y, Freiman TM, Maegdefessel L, Plate KH, Mittelbronn M, Uchida S, Künne C, Stellos K, Schermuly RT, Weissmann N, Devraj K, Wittig I, Boon RA, Dimmeler S, Pullamsetti SS, Looso M, Miller FJ Jr, Brandes RP. Leisegang MS, et al. Among authors: valasarajan c. Circulation. 2017 Jul 4;136(1):65-79. doi: 10.1161/CIRCULATIONAHA.116.026991. Epub 2017 Mar 28. Circulation. 2017. PMID: 28351900 Free PMC article.
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension.
Dabral S, Muecke C, Valasarajan C, Schmoranzer M, Wietelmann A, Semenza GL, Meister M, Muley T, Seeger-Nukpezah T, Samakovlis C, Weissmann N, Grimminger F, Seeger W, Savai R, Pullamsetti SS. Dabral S, et al. Among authors: valasarajan c. Nat Commun. 2019 May 13;10(1):2130. doi: 10.1038/s41467-019-10044-z. Nat Commun. 2019. PMID: 31086178 Free PMC article.
Long Noncoding RNA TYKRIL Plays a Role in Pulmonary Hypertension via the p53-mediated Regulation of PDGFRβ.
Zehendner CM, Valasarajan C, Werner A, Boeckel JN, Bischoff FC, John D, Weirick T, Glaser SF, Rossbach O, Jaé N, Demolli S, Khassafi F, Yuan K, de Jesus Perez VA, Michalik KM, Chen W, Seeger W, Guenther A, Wasnick RM, Uchida S, Zeiher AM, Dimmeler S, Pullamsetti SS. Zehendner CM, et al. Among authors: valasarajan c. Am J Respir Crit Care Med. 2020 Nov 15;202(10):1445-1457. doi: 10.1164/rccm.201910-2041OC. Am J Respir Crit Care Med. 2020. PMID: 32634060 Free PMC article.
Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension.
Chelladurai P, Kuenne C, Bourgeois A, Günther S, Valasarajan C, Cherian AV, Rottier RJ, Romanet C, Weigert A, Boucherat O, Eichstaedt CA, Ruppert C, Guenther A, Braun T, Looso M, Savai R, Seeger W, Bauer UM, Bonnet S, Pullamsetti SS. Chelladurai P, et al. Among authors: valasarajan c. Sci Transl Med. 2022 Jun 8;14(648):eabe5407. doi: 10.1126/scitranslmed.abe5407. Epub 2022 Jun 8. Sci Transl Med. 2022. PMID: 35675437
Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system.
Weigert A, Zheng X, Nenzel A, Turkowski K, Günther S, Strack E, Sirait-Fischer E, Elwakeel E, Kur IM, Nikam VS, Valasarajan C, Winter H, Wissgott A, Voswinkel R, Grimminger F, Brüne B, Seeger W, Pullamsetti SS, Savai R. Weigert A, et al. Among authors: valasarajan c. Nat Commun. 2022 Oct 14;13(1):6078. doi: 10.1038/s41467-022-33458-8. Nat Commun. 2022. PMID: 36241617 Free PMC article.
HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex.
Leisegang MS, Bains JK, Seredinski S, Oo JA, Krause NM, Kuo CC, Günther S, Sentürk Cetin N, Warwick T, Cao C, Boos F, Izquierdo Ponce J, Haydar S, Bednarz R, Valasarajan C, Fuhrmann DC, Preussner J, Looso M, Pullamsetti SS, Schulz MH, Jonker HRA, Richter C, Rezende F, Gilsbach R, Pflüger-Müller B, Wittig I, Grummt I, Ribarska T, Costa IG, Schwalbe H, Brandes RP. Leisegang MS, et al. Among authors: valasarajan c. Nat Commun. 2022 Nov 2;13(1):6563. doi: 10.1038/s41467-022-34252-2. Nat Commun. 2022. PMID: 36323673 Free PMC article.
ATP citrate lyase drives vascular remodeling in systemic and pulmonary vascular diseases through metabolic and epigenetic changes.
Grobs Y, Romanet C, Lemay SE, Bourgeois A, Voisine P, Theberge C, Sauvaget M, Breuils-Bonnet S, Martineau S, El Kabbout R, Valasarajan C, Chelladurai P, Pelletier A, Mougin M, Dumais E, Perron J, Flamand N, Potus F, Provencher S, Pullamsetti SS, Boucherat O, Bonnet S. Grobs Y, et al. Among authors: valasarajan c. Sci Transl Med. 2024 Dec 11;16(777):eado7824. doi: 10.1126/scitranslmed.ado7824. Epub 2024 Dec 11. Sci Transl Med. 2024. PMID: 39661707
Hematopoietic PI3Kδ deficiency aggravates murine atherosclerosis through impairment of Tregs.
Zierden M, Berghausen EM, Gnatzy-Feik L, Millarg C, Picard FSR, Kiljan M, Geißen S, Polykratis A, Zimmermann L, Nies RJ, Pasparakis M, Baldus S, Valasarajan C, Pullamsetti SS, Winkels H, Vantler M, Rosenkranz S. Zierden M, et al. Among authors: valasarajan c. JCI Insight. 2024 Nov 22;9(22):e155626. doi: 10.1172/jci.insight.155626. JCI Insight. 2024. PMID: 39378110 Free PMC article.
Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension.
Khassafi F, Chelladurai P, Valasarajan C, Nayakanti SR, Martineau S, Sommer N, Yokokawa T, Boucherat O, Kamal A, Kiely DG, Swift AJ, Alabed S, Omura J, Breuils-Bonnet S, Kuenne C, Potus F, Günther S, Savai R, Seeger W, Looso M, Lawrie A, Zaugg JB, Tello K, Provencher S, Bonnet S, Pullamsetti SS. Khassafi F, et al. Among authors: valasarajan c. Nat Cardiovasc Res. 2023 Oct;2(10):917-936. doi: 10.1038/s44161-023-00338-3. Epub 2023 Sep 28. Nat Cardiovasc Res. 2023. PMID: 39196250 Free PMC article.
11 results