Zhao L - Search Results

1

Structure-constrained endomorphin analogs display differential antinociceptive mechanisms in mice after spinal administration.

Wang Y, Zhou J, Liu X, Zhao L, Wang Z, Zhang X, Wang K, Wang L, Wang R. Wang Y, et al. Among authors: zhao l. Peptides. 2017 May;91:40-48. doi: 10.1016/j.peptides.2017.03.009. Epub 2017 Mar 29. Peptides. 2017. PMID: 28363796

2

The asymmetric synthesis of CF3-containing spiro[pyrrolidin-3,2'-oxindole] through the organocatalytic 1,3-dipolar cycloaddition reaction.

Ma M, Zhu Y, Sun Q, Li X, Su J, Zhao L, Zhao Y, Qiu S, Yan W, Wang K, Wang R. Ma M, et al. Among authors: zhao y, zhao l. Chem Commun (Camb). 2015 May 25;51(42):8789-92. doi: 10.1039/c4cc10216a. Chem Commun (Camb). 2015. PMID: 25915470

3

Endomorphin-1 analogues (MELs) penetrate the blood-brain barrier and exhibit good analgesic effects with minimal side effects.

Wang Y, Liu X, Wang D, Yang J, Zhao L, Yu J, Wang R. Wang Y, et al. Among authors: zhao l. Neuropharmacology. 2015 Oct;97:312-21. doi: 10.1016/j.neuropharm.2015.06.010. Epub 2015 Jun 24. Neuropharmacology. 2015. PMID: 26116761

4

Design, synthesis, and evaluation of new endomorphin analogs with enhanced central antinociception after peripheral administration.

Liu X, Zhao L, Wang Y, Mou L, Yang J, Zhang Y, Wang D, Wang R. Liu X, et al. Among authors: zhao l. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5393-7. doi: 10.1016/j.bmcl.2015.09.025. Epub 2015 Sep 11. Bioorg Med Chem Lett. 2015. PMID: 26403932

5

Construction of Vicinal Tetrasubstituted Stereocenters with a C-F Bond through a Catalytic Enantioselective Detrifluoroacetylative Mannich Reaction.

Liu X, Zhang J, Zhao L, Ma S, Yang D, Yan W, Wang R. Liu X, et al. Among authors: zhao l. J Org Chem. 2015 Dec 18;80(24):12651-8. doi: 10.1021/acs.joc.5b02238. Epub 2015 Dec 4. J Org Chem. 2015. PMID: 26574779

6

Endomorphin-1 analogs containing α-methyl-β-amino acids exhibit potent analgesic activity after peripheral administration.

Wang Y, Yang J, Liu X, Zhao L, Yang D, Zhou J, Wang D, Mou L, Wang R. Wang Y, et al. Among authors: zhao l. Org Biomol Chem. 2017 Jun 14;15(23):4951-4955. doi: 10.1039/c7ob01115f. Org Biomol Chem. 2017. PMID: 28567467

7

MEL-N16: A Series of Novel Endomorphin Analogs with Good Analgesic Activity and a Favorable Side Effect Profile.

Liu X, Zhao L, Wang Y, Zhou J, Wang D, Zhang Y, Zhang X, Wang Z, Yang D, Mou L, Wang R. Liu X, et al. Among authors: zhao l. ACS Chem Neurosci. 2017 Oct 18;8(10):2180-2193. doi: 10.1021/acschemneuro.7b00097. Epub 2017 Aug 10. ACS Chem Neurosci. 2017. PMID: 28732166

8

Visible-Light-Driven, Copper-Catalyzed Decarboxylative C(sp³ )-H Alkylation of Glycine and Peptides.

Wang C, Guo M, Qi R, Shang Q, Liu Q, Wang S, Zhao L, Wang R, Xu Z. Wang C, et al. Among authors: zhao l. Angew Chem Int Ed Engl. 2018 Nov 26;57(48):15841-15846. doi: 10.1002/anie.201809400. Epub 2018 Nov 7. Angew Chem Int Ed Engl. 2018. PMID: 30296349

9

MEL endomorphins act as potent inflammatory analgesics with the inhibition of activated non-neuronal cells and modulation of pro-inflammatory cytokines.

Cui JM, Zhao L, Wang ZJ, Ma MT, Wang Y, Luo KY, Wang LQ, Wei S, Zhang XH, Han CZ, Liu X, Wang R. Cui JM, et al. Among authors: zhao l. Neuropharmacology. 2020 May 15;168:107992. doi: 10.1016/j.neuropharm.2020.107992. Epub 2020 Feb 6. Neuropharmacology. 2020. PMID: 32036072

10

Design, synthesis, and biological activity of new endomorphin analogs with multi-site modifications.

Zhao L, Luo K, Wang Z, Wang Y, Zhang X, Yang D, Ma M, Zhou J, Cui J, Wang J, Han CZ, Liu X, Wang R. Zhao L, et al. Bioorg Med Chem. 2020 May 1;28(9):115438. doi: 10.1016/j.bmc.2020.115438. Epub 2020 Mar 13. Bioorg Med Chem. 2020. PMID: 32199689

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