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Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4.
Xin X, Rodrigues M, Umapathi M, Kashiwabuchi F, Ma T, Babapoor-Farrokhran S, Wang S, Hu J, Bhutto I, Welsbie DS, Duh EJ, Handa JT, Eberhart CG, Lutty G, Semenza GL, Montaner S, Sodhi A. Xin X, et al. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3425-34. doi: 10.1073/pnas.1217091110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959876 Free PMC article.
Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells.
Maruotti J, Sripathi SR, Bharti K, Fuller J, Wahlin KJ, Ranganathan V, Sluch VM, Berlinicke CA, Davis J, Kim C, Zhao L, Wan J, Qian J, Corneo B, Temple S, Dubey R, Olenyuk BZ, Bhutto I, Lutty GA, Zack DJ. Maruotti J, et al. Among authors: lutty ga. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):10950-5. doi: 10.1073/pnas.1422818112. Epub 2015 Aug 12. Proc Natl Acad Sci U S A. 2015. PMID: 26269569 Free PMC article.
Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy.
Babapoor-Farrokhran S, Jee K, Puchner B, Hassan SJ, Xin X, Rodrigues M, Kashiwabuchi F, Ma T, Hu K, Deshpande M, Daoud Y, Solomon S, Wenick A, Lutty GA, Semenza GL, Montaner S, Sodhi A. Babapoor-Farrokhran S, et al. Among authors: lutty ga. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):E3030-9. doi: 10.1073/pnas.1423765112. Epub 2015 May 26. Proc Natl Acad Sci U S A. 2015. PMID: 26039997 Free PMC article.
183 results