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The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression.
Becchetti A, Crescioli S, Zanieri F, Petroni G, Mercatelli R, Coppola S, Gasparoli L, D'Amico M, Pillozzi S, Crociani O, Stefanini M, Fiore A, Carraresi L, Morello V, Manoli S, Brizzi MF, Ricci D, Rinaldi M, Masi A, Schmidt T, Quercioli F, Defilippi P, Arcangeli A. Becchetti A, et al. Among authors: stefanini m. Sci Signal. 2017 Apr 4;10(473):eaaf3236. doi: 10.1126/scisignal.aaf3236. Sci Signal. 2017. PMID: 28377405 Free article.
hERG1 channels regulate VEGF-A secretion in human gastric cancer: clinicopathological correlations and therapeutical implications.
Crociani O, Lastraioli E, Boni L, Pillozzi S, Romoli MR, D'Amico M, Stefanini M, Crescioli S, Masi A, Taddei A, Bencini L, Bernini M, Farsi M, Beghelli S, Scarpa A, Messerini L, Tomezzoli A, Vindigni C, Morgagni P, Saragoni L, Giommoni E, Gasperoni S, Di Costanzo F, Roviello F, De Manzoni G, Bechi P, Arcangeli A. Crociani O, et al. Among authors: stefanini m. Clin Cancer Res. 2014 Mar 15;20(6):1502-12. doi: 10.1158/1078-0432.CCR-13-2633. Epub 2014 Jan 21. Clin Cancer Res. 2014. PMID: 24449824
Harnessing the hERG1/β1 Integrin Complex via a Novel Bispecific Single-chain Antibody: An Effective Strategy against Solid Cancers.
Duranti C, Iorio J, Lottini T, Lastraioli E, Crescioli S, Bagni G, Lulli M, Capitani C, Bouazzi R, Stefanini M, Carraresi L, Iamele L, De Jonge H, Arcangeli A. Duranti C, et al. Among authors: stefanini m. Mol Cancer Ther. 2021 Aug;20(8):1338-1349. doi: 10.1158/1535-7163.MCT-20-1111. Epub 2021 May 27. Mol Cancer Ther. 2021. PMID: 34045227
655 results