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Page 1
Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.
von Hundelshausen P, Agten SM, Eckardt V, Blanchet X, Schmitt MM, Ippel H, Neideck C, Bidzhekov K, Leberzammer J, Wichapong K, Faussner A, Drechsler M, Grommes J, van Geffen JP, Li H, Ortega-Gomez A, Megens RT, Naumann R, Dijkgraaf I, Nicolaes GA, Döring Y, Soehnlein O, Lutgens E, Heemskerk JW, Koenen RR, Mayo KH, Hackeng TM, Weber C. von Hundelshausen P, et al. Among authors: lutgens e. Sci Transl Med. 2017 Apr 5;9(384):eaah6650. doi: 10.1126/scitranslmed.aah6650. Sci Transl Med. 2017. PMID: 28381538
The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling.
Donners MM, Beckers L, Lievens D, Munnix I, Heemskerk J, Janssen BJ, Wijnands E, Cleutjens J, Zernecke A, Weber C, Ahonen CL, Benbow U, Newby AC, Noelle RJ, Daemen MJ, Lutgens E. Donners MM, et al. Among authors: lutgens e. Blood. 2008 May 1;111(9):4596-604. doi: 10.1182/blood-2007-05-088906. Epub 2008 Jan 14. Blood. 2008. PMID: 18195092 Free PMC article.
Complementary roles of platelets and coagulation in thrombus formation on plaques acutely ruptured by targeted ultrasound treatment: a novel intravital model.
Kuijpers MJ, Gilio K, Reitsma S, Nergiz-Unal R, Prinzen L, Heeneman S, Lutgens E, van Zandvoort MA, Nieswandt B, Egbrink MG, Heemskerk JW. Kuijpers MJ, et al. Among authors: lutgens e. J Thromb Haemost. 2009 Jan;7(1):152-61. doi: 10.1111/j.1538-7836.2008.03186.x. Epub 2008 Oct 7. J Thromb Haemost. 2009. PMID: 18983512 Free article.
Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile.
Lutgens E, Lievens D, Beckers L, Wijnands E, Soehnlein O, Zernecke A, Seijkens T, Engel D, Cleutjens J, Keller AM, Naik SH, Boon L, Oufella HA, Mallat Z, Ahonen CL, Noelle RJ, de Winther MP, Daemen MJ, Biessen EA, Weber C. Lutgens E, et al. J Exp Med. 2010 Feb 15;207(2):391-404. doi: 10.1084/jem.20091293. Epub 2010 Jan 25. J Exp Med. 2010. PMID: 20100871 Free PMC article.
CD40L-CD40 fuel ignites obesity.
Lutgens E, Poggi M, Weber C. Lutgens E, et al. Thromb Haemost. 2010 Apr;103(4):694-5. doi: 10.1160/TH10-03-0146. Epub 2010 Mar 10. Thromb Haemost. 2010. PMID: 20216980 No abstract available.
Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis.
Lievens D, Zernecke A, Seijkens T, Soehnlein O, Beckers L, Munnix IC, Wijnands E, Goossens P, van Kruchten R, Thevissen L, Boon L, Flavell RA, Noelle RJ, Gerdes N, Biessen EA, Daemen MJ, Heemskerk JW, Weber C, Lutgens E. Lievens D, et al. Among authors: lutgens e. Blood. 2010 Nov 18;116(20):4317-27. doi: 10.1182/blood-2010-01-261206. Epub 2010 Aug 12. Blood. 2010. PMID: 20705757 Free PMC article.
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