Huang S - Search Results

1

Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the gefitinib-resistant non-small cell lung cancers (NSCLC).

Song Z, Huang S, Yu H, Jiang Y, Wang C, Meng Q, Shu X, Sun H, Liu K, Li Y, Ma X. Song Z, et al. Among authors: huang s. Eur J Med Chem. 2017 Jun 16;133:329-339. doi: 10.1016/j.ejmech.2017.03.083. Epub 2017 Apr 2. Eur J Med Chem. 2017. PMID: 28395219

2

Challenges and Perspectives on the Development of Small-Molecule EGFR Inhibitors against T790M-Mediated Resistance in Non-Small-Cell Lung Cancer.

Song Z, Ge Y, Wang C, Huang S, Shu X, Liu K, Zhou Y, Ma X. Song Z, et al. Among authors: huang s. J Med Chem. 2016 Jul 28;59(14):6580-94. doi: 10.1021/acs.jmedchem.5b00840. Epub 2016 Feb 26. J Med Chem. 2016. PMID: 26882288

3

Synthesis and biological evaluation of benzophenone derivatives as potential HIV-1 inhibitors.

Song Z, Wang P, Huang S, Wang C, Wang R, Yang L, Zhen Y, Liu K, Zheng Y, Ma X. Song Z, et al. Among authors: huang s. Med Chem. 2016 Nov 11. Online ahead of print. Med Chem. 2016. PMID: 27834135

4

Structural optimization of diphenylpyrimidine derivatives (DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B leukemia cell lines.

Zhao D, Huang S, Qu M, Wang C, Liu Z, Li Z, Peng J, Liu K, Li Y, Ma X, Shu X. Zhao D, et al. Among authors: huang s. Eur J Med Chem. 2017 Jan 27;126:444-455. doi: 10.1016/j.ejmech.2016.11.047. Epub 2016 Nov 23. Eur J Med Chem. 2017. PMID: 27912175

5

Structural optimization of diphenylpyrimidine scaffold as potent and selective epidermal growth factor receptor inhibitors against L858R/T790M resistance mutation in nonsmall cell lung cancer.

Yi Y, Wang L, Zhao D, Huang S, Wang C, Liu Z, Sun H, Liu K, Ma X, Li Y. Yi Y, et al. Among authors: huang s. Chem Biol Drug Des. 2018 Dec;92(6):1988-1997. doi: 10.1111/cbdd.13370. Epub 2018 Aug 26. Chem Biol Drug Des. 2018. PMID: 30030903

6

Novel 4-anilinoquinazoline derivatives featuring an 1-adamantyl moiety as potent EGFR inhibitors with enhanced activity against NSCLC cell lines.

Yu H, Li Y, Ge Y, Song Z, Wang C, Huang S, Jin Y, Han X, Zhen Y, Liu K, Zhou Y, Ma X. Yu H, et al. Among authors: huang s. Eur J Med Chem. 2016 Mar 3;110:195-203. doi: 10.1016/j.ejmech.2016.01.045. Epub 2016 Jan 26. Eur J Med Chem. 2016. PMID: 26829280

7

7-O-geranylquercetin contributes to reverse P-gp-mediated adriamycin resistance in breast cancer.

Zhang E, Liu J, Shi L, Guo X, Liang Z, Zuo J, Xu H, Wang H, Shu X, Huang S, Zhang S, Kang X, Zhen Y. Zhang E, et al. Among authors: huang s. Life Sci. 2019 Dec 1;238:116938. doi: 10.1016/j.lfs.2019.116938. Epub 2019 Oct 5. Life Sci. 2019. PMID: 31593704

8

Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.

Jin J, Zhou M, Wang X, Liu M, Huang H, Yan F, Yu Z, Shu X, Huo X, Feng L, Zhang B, Huang S, Deng S, Wang C, Ma X. Jin J, et al. Among authors: huang s, huang h. Fitoterapia. 2021 Jan;148:104779. doi: 10.1016/j.fitote.2020.104779. Epub 2020 Nov 24. Fitoterapia. 2021. PMID: 33242535

9

Bioactive metabolites of Schisanlactone E transformed by Cunninghamella blakesleana AS 3.970.

Mai ZP, Wang C, Wang Y, Zhang HL, Zhang BJ, Wang W, Huo XK, Huang SS, Wang CY, Liu KX, Ma XC, Wang XB. Mai ZP, et al. Fitoterapia. 2014 Dec;99:352-61. doi: 10.1016/j.fitote.2014.10.016. Epub 2014 Oct 30. Fitoterapia. 2014. PMID: 25451796

10

Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway.

Tang N, Shi L, Yu Z, Dong P, Wang C, Huo X, Zhang B, Huang S, Deng S, Liu K, Ma T, Wang X, Wu L, Ma XC. Tang N, et al. Among authors: huang s. Oncotarget. 2016 Jan 19;7(3):3533-47. doi: 10.18632/oncotarget.6514. Oncotarget. 2016. PMID: 26657289 Free PMC article.

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