Critical role for complement receptor C5aR2 in the pathogenesis of renal ischemia-reperfusion injury.
Poppelaars F, van Werkhoven MB, Kotimaa J, Veldhuis ZJ, Ausema A, Broeren SGM, Damman J, Hempel JC, Leuvenink HGD, Daha MR, van Son WJ, van Kooten C, van Os RP, Hillebrands JL, Seelen MA.
Poppelaars F, et al. Among authors: ausema a.
FASEB J. 2017 Jul;31(7):3193-3204. doi: 10.1096/fj.201601218R. Epub 2017 Apr 10.
FASEB J. 2017.
PMID: 28396344
These studies reveal the importance of C5aR2 in renal IR injury. They further show that C5aR2 is a functional receptor, rather than a decoy receptor, and may provide a new target for intervention.-Poppelaars, F., van Werkhoven, M. B., Kotimaa, J., Veldhuis, Z …
These studies reveal the importance of C5aR2 in renal IR injury. They further show that C5aR2 is a functional receptor, rather than …