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PIK3CA mutant tumors depend on oxoglutarate dehydrogenase.
Ilic N, Birsoy K, Aguirre AJ, Kory N, Pacold ME, Singh S, Moody SE, DeAngelo JD, Spardy NA, Freinkman E, Weir BA, Tsherniak A, Cowley GS, Root DE, Asara JM, Vazquez F, Widlund HR, Sabatini DM, Hahn WC. Ilic N, et al. Among authors: singh s. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3434-E3443. doi: 10.1073/pnas.1617922114. Epub 2017 Apr 10. Proc Natl Acad Sci U S A. 2017. PMID: 28396387 Free PMC article.
The chemistry of the S-nitrosoglutathione/glutathione system.
Singh SP, Wishnok JS, Keshive M, Deen WM, Tannenbaum SR. Singh SP, et al. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14428-33. doi: 10.1073/pnas.93.25.14428. Proc Natl Acad Sci U S A. 1996. PMID: 8962068 Free PMC article.
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