Leippe P - Search Results

1

Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors.

Levitz J, Broichhagen J, Leippe P, Konrad D, Trauner D, Isacoff EY. Levitz J, et al. Among authors: leippe p. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3546-E3554. doi: 10.1073/pnas.1619652114. Epub 2017 Apr 10. Proc Natl Acad Sci U S A. 2017. PMID: 28396447 Free PMC article.

2

Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand.

Broichhagen J, Damijonaitis A, Levitz J, Sokol KR, Leippe P, Konrad D, Isacoff EY, Trauner D. Broichhagen J, et al. Among authors: leippe p. ACS Cent Sci. 2015 Oct 28;1(7):383-93. doi: 10.1021/acscentsci.5b00260. Epub 2015 Oct 16. ACS Cent Sci. 2015. PMID: 27162996 Free PMC article.

3

Optical Control of a Delayed Rectifier and a Two-Pore Potassium Channel with a Photoswitchable Bupivacaine.

Leippe P, Winter N, Sumser MP, Trauner D. Leippe P, et al. ACS Chem Neurosci. 2018 Dec 19;9(12):2886-2891. doi: 10.1021/acschemneuro.8b00279. Epub 2018 Aug 14. ACS Chem Neurosci. 2018. PMID: 30001098

4

Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors.

Leippe P, Broichhagen J, Cailliau K, Mougel A, Morel M, Dissous C, Trauner D, Vicogne J. Leippe P, et al. Angew Chem Int Ed Engl. 2020 Apr 20;59(17):6720-6723. doi: 10.1002/anie.201915352. Epub 2020 Mar 4. Angew Chem Int Ed Engl. 2020. PMID: 31872568

5

Specificity and Speed: Tethered Photopharmacology.

Leippe P, Koehler Leman J, Trauner D. Leippe P, et al. Biochemistry. 2017 Oct 3;56(39):5214-5220. doi: 10.1021/acs.biochem.7b00687. Epub 2017 Sep 14. Biochemistry. 2017. PMID: 28876905 Review.

6

Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor γ (PPARγ).

Hinnah K, Willems S, Morstein J, Heering J, Hartrampf FWW, Broichhagen J, Leippe P, Merk D, Trauner D. Hinnah K, et al. Among authors: leippe p. J Med Chem. 2020 Oct 8;63(19):10908-10920. doi: 10.1021/acs.jmedchem.0c00654. Epub 2020 Sep 21. J Med Chem. 2020. PMID: 32886507

7

Synthesis of Photoswitchable Δ⁹-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling.

Westphal MV, Schafroth MA, Sarott RC, Imhof MA, Bold CP, Leippe P, Dhopeshwarkar A, Grandner JM, Katritch V, Mackie K, Trauner D, Carreira EM, Frank JA. Westphal MV, et al. Among authors: leippe p. J Am Chem Soc. 2017 Dec 20;139(50):18206-18212. doi: 10.1021/jacs.7b06456. Epub 2017 Dec 12. J Am Chem Soc. 2017. PMID: 29161035

8

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology.

Podewin T, Ast J, Broichhagen J, Fine NHF, Nasteska D, Leippe P, Gailer M, Buenaventura T, Kanda N, Jones BJ, M'Kadmi C, Baneres JL, Marie J, Tomas A, Trauner D, Hoffmann-Röder A, Hodson DJ. Podewin T, et al. Among authors: leippe p. ACS Cent Sci. 2018 Feb 28;4(2):166-179. doi: 10.1021/acscentsci.7b00237. Epub 2018 Jan 16. ACS Cent Sci. 2018. PMID: 29532016 Free PMC article.

9

Oxidative Approach Enables Efficient Access to Cyclic Azobenzenes.

Maier MS, Hüll K, Reynders M, Matsuura BS, Leippe P, Ko T, Schäffer L, Trauner D. Maier MS, et al. Among authors: leippe p. J Am Chem Soc. 2019 Oct 30;141(43):17295-17304. doi: 10.1021/jacs.9b08794. Epub 2019 Oct 17. J Am Chem Soc. 2019. PMID: 31584272

10

Designing azobenzene-based tools for controlling neurotransmission.

Leippe P, Frank JA. Leippe P, et al. Curr Opin Struct Biol. 2019 Aug;57:23-30. doi: 10.1016/j.sbi.2019.01.022. Epub 2019 Feb 28. Curr Opin Struct Biol. 2019. PMID: 30825844 Review.

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