Leban J - Search Results

1

Inhibitors of dual-specificity tyrosine phosphorylation-regulated kinases (DYRK) exert a strong anti-herpesviral activity.

Hutterer C, Milbradt J, Hamilton S, Zaja M, Leban J, Henry C, Vitt D, Steingruber M, Sonntag E, Zeitträger I, Bahsi H, Stamminger T, Rawlinson W, Strobl S, Marschall M. Hutterer C, et al. Among authors: leban j. Antiviral Res. 2017 Jul;143:113-121. doi: 10.1016/j.antiviral.2017.04.003. Epub 2017 Apr 9. Antiviral Res. 2017. PMID: 28400201

2

Assessment of drug candidates for broad-spectrum antiviral therapy targeting cellular pyrimidine biosynthesis.

Marschall M, Niemann I, Kosulin K, Bootz A, Wagner S, Dobner T, Herz T, Kramer B, Leban J, Vitt D, Stamminger T, Hutterer C, Strobl S. Marschall M, et al. Among authors: leban j. Antiviral Res. 2013 Dec;100(3):640-8. doi: 10.1016/j.antiviral.2013.10.003. Epub 2013 Oct 20. Antiviral Res. 2013. PMID: 24149002

3

Human dihydroorotate dehydrogenase inhibitors, a novel approach for the treatment of autoimmune and inflammatory diseases.

Leban J, Vitt D. Leban J, et al. Arzneimittelforschung. 2011;61(1):66-72. doi: 10.1055/s-0031-1296169. Arzneimittelforschung. 2011. PMID: 21355448 Review.

4

The NF-kappaB inhibitor SC75741 protects mice against highly pathogenic avian influenza A virus.

Haasbach E, Reiling SJ, Ehrhardt C, Droebner K, Rückle A, Hrincius ER, Leban J, Strobl S, Vitt D, Ludwig S, Planz O. Haasbach E, et al. Among authors: leban j. Antiviral Res. 2013 Sep;99(3):336-44. doi: 10.1016/j.antiviral.2013.06.008. Epub 2013 Jun 28. Antiviral Res. 2013. PMID: 23811282

5

DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.

Gruber W, Hutzinger M, Elmer DP, Parigger T, Sternberg C, Cegielkowski L, Zaja M, Leban J, Michel S, Hamm S, Vitt D, Aberger F. Gruber W, et al. Among authors: leban j. Oncotarget. 2016 Feb 9;7(6):7134-48. doi: 10.18632/oncotarget.6910. Oncotarget. 2016. PMID: 26784250 Free PMC article.

6

2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1δ/ε.

Bischof J, Leban J, Zaja M, Grothey A, Radunsky B, Othersen O, Strobl S, Vitt D, Knippschild U. Bischof J, et al. Among authors: leban j. Amino Acids. 2012 Oct;43(4):1577-91. doi: 10.1007/s00726-012-1234-x. Epub 2012 Feb 14. Amino Acids. 2012. PMID: 22331384 Free PMC article.

7

The NF-κB inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance.

Ehrhardt C, Rückle A, Hrincius ER, Haasbach E, Anhlan D, Ahmann K, Banning C, Reiling SJ, Kühn J, Strobl S, Vitt D, Leban J, Planz O, Ludwig S. Ehrhardt C, et al. Among authors: leban j. Cell Microbiol. 2013 Jul;15(7):1198-211. doi: 10.1111/cmi.12108. Epub 2013 Feb 5. Cell Microbiol. 2013. PMID: 23320394

8

A new small molecule for treating inflammation and chorioretinal neovascularization in relapsing-remitting and chronic experimental autoimmune uveitis.

Diedrichs-Möhring M, Leban J, Strobl S, Obermayr F, Wildner G. Diedrichs-Möhring M, et al. Among authors: leban j. Invest Ophthalmol Vis Sci. 2014 Dec 16;56(2):1147-57. doi: 10.1167/iovs.14-15518. Invest Ophthalmol Vis Sci. 2014. PMID: 25515581

9

Difluoro-dioxolo-benzoimidazol-benzamides as potent inhibitors of CK1δ and ε with nanomolar inhibitory activity on cancer cell proliferation.

Richter J, Bischof J, Zaja M, Kohlhof H, Othersen O, Vitt D, Alscher V, Pospiech I, García-Reyes B, Berg S, Leban J, Knippschild U. Richter J, et al. Among authors: leban j. J Med Chem. 2014 Oct 9;57(19):7933-46. doi: 10.1021/jm500600b. Epub 2014 Sep 17. J Med Chem. 2014. PMID: 25191940

10

A novel class of potent NF-kappaB signaling inhibitors.

Leban J, Baierl M, Mies J, Trentinaglia V, Rath S, Kronthaler K, Wolf K, Gotschlich A, Seifert MH. Leban J, et al. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5858-62. doi: 10.1016/j.bmcl.2007.08.022. Epub 2007 Aug 15. Bioorg Med Chem Lett. 2007. PMID: 17869512

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