Debets R - Search Results

1

Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities.

Van Caeneghem Y, De Munter S, Tieppo P, Goetgeluk G, Weening K, Verstichel G, Bonte S, Taghon T, Leclercq G, Kerre T, Debets R, Vermijlen D, Abken H, Vandekerckhove B. Van Caeneghem Y, et al. Among authors: debets r. Oncoimmunology. 2017 Jan 19;6(3):e1283460. doi: 10.1080/2162402X.2017.1283460. eCollection 2017. Oncoimmunology. 2017. PMID: 28405508 Free PMC article.

2

CAR-T cells and solid tumors: tuning T cells to challenge an inveterate foe.

Gilham DE, Debets R, Pule M, Hawkins RE, Abken H. Gilham DE, et al. Among authors: debets r. Trends Mol Med. 2012 Jul;18(7):377-84. doi: 10.1016/j.molmed.2012.04.009. Epub 2012 May 19. Trends Mol Med. 2012. PMID: 22613370 Review.

3

Intra-tumoral production of IL18, but not IL12, by TCR-engineered T cells is non-toxic and counteracts immune evasion of solid tumors.

Kunert A, Chmielewski M, Wijers R, Berrevoets C, Abken H, Debets R. Kunert A, et al. Among authors: debets r. Oncoimmunology. 2017 Oct 11;7(1):e1378842. doi: 10.1080/2162402X.2017.1378842. eCollection 2017. Oncoimmunology. 2017. PMID: 29296541 Free PMC article.

4

An oncolytic adenovirus redirected with a tumor-specific T-cell receptor.

Sebestyen Z, de Vrij J, Magnusson M, Debets R, Willemsen R. Sebestyen Z, et al. Among authors: debets r. Cancer Res. 2007 Dec 1;67(23):11309-16. doi: 10.1158/0008-5472.CAN-07-0739. Cancer Res. 2007. PMID: 18056457

5

T cell receptor gene therapy: strategies for optimizing transgenic TCR pairing.

Govers C, Sebestyén Z, Coccoris M, Willemsen RA, Debets R. Govers C, et al. Among authors: debets r. Trends Mol Med. 2010 Feb;16(2):77-87. doi: 10.1016/j.molmed.2009.12.004. Epub 2010 Feb 1. Trends Mol Med. 2010. PMID: 20122868 Review.

6

TCR gene-engineered T cell: limited T cell activation and combined use of IL-15 and IL-21 ensure minimal differentiation and maximal antigen-specificity.

Pouw N, Treffers-Westerlaken E, Mondino A, Lamers C, Debets R. Pouw N, et al. Among authors: debets r. Mol Immunol. 2010 Apr;47(7-8):1411-20. doi: 10.1016/j.molimm.2010.02.022. Mol Immunol. 2010. PMID: 20303179

7

Development of adoptive cell therapy for cancer: a clinical perspective.

Hawkins RE, Gilham DE, Debets R, Eshhar Z, Taylor N, Abken H, Schumacher TN, ATTACK Consortium. Hawkins RE, et al. Among authors: debets r. Hum Gene Ther. 2010 Jun;21(6):665-72. doi: 10.1089/hum.2010.086. Hum Gene Ther. 2010. PMID: 20408760 Review.

8

Chimeric antigen receptors for T-cell based therapy.

Cheadle EJ, Sheard V, Hombach AA, Chmielewski M, Riet T, Berrevoets C, Schooten E, Lamers C, Abken H, Debets R, Gilham DE. Cheadle EJ, et al. Among authors: debets r. Methods Mol Biol. 2012;907:645-66. doi: 10.1007/978-1-61779-974-7_36. Methods Mol Biol. 2012. PMID: 22907378

9

T cell receptor-engineered T cells to treat solid tumors: T cell processing toward optimal T cell fitness.

Lamers CH, van Steenbergen-Langeveld S, van Brakel M, Groot-van Ruijven CM, van Elzakker PM, van Krimpen B, Sleijfer S, Debets R. Lamers CH, et al. Among authors: debets r. Hum Gene Ther Methods. 2014 Dec;25(6):345-57. doi: 10.1089/hgtb.2014.051. Hum Gene Ther Methods. 2014. PMID: 25423330 Free PMC article.

10

T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors.

Manzo T, Sturmheit T, Basso V, Petrozziello E, Hess Michelini R, Riba M, Freschi M, Elia AR, Grioni M, Curnis F, Protti MP, Schumacher TN, Debets R, Swartz MA, Corti A, Bellone M, Mondino A. Manzo T, et al. Among authors: debets r. Cancer Res. 2017 Feb 1;77(3):658-671. doi: 10.1158/0008-5472.CAN-16-0725. Epub 2016 Nov 21. Cancer Res. 2017. PMID: 27872095

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