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2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G. Romagnoli R, et al. Among authors: oliva p. Eur J Med Chem. 2018 Jan 1;143:683-698. doi: 10.1016/j.ejmech.2017.11.096. Eur J Med Chem. 2018. PMID: 29220790 Free PMC article.
Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells.
Romagnoli R, Prencipe F, Lopez-Cara LC, Oliva P, Baraldi S, Baraldi PG, Estévez-Sarmiento F, Quintana J, Estévez F. Romagnoli R, et al. Among authors: oliva p. J Enzyme Inhib Med Chem. 2018 Dec;33(1):727-742. doi: 10.1080/14756366.2018.1450749. J Enzyme Inhib Med Chem. 2018. PMID: 29620429 Free PMC article.
3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
Romagnoli R, Prencipe F, Oliva P, Baraldi S, Baraldi PG, Brancale A, Ferla S, Hamel E, Bortolozzi R, Viola G. Romagnoli R, et al. Among authors: oliva p. Bioorg Chem. 2018 Oct;80:361-374. doi: 10.1016/j.bioorg.2018.06.037. Epub 2018 Jun 30. Bioorg Chem. 2018. PMID: 29986184 Free article.
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors.
Romagnoli R, Prencipe F, Oliva P, Baraldi S, Baraldi PG, Schiaffino Ortega S, Chayah M, Kimatrai Salvador M, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Mattiuzzo E, Viola G. Romagnoli R, et al. Among authors: oliva p. J Med Chem. 2019 Feb 14;62(3):1274-1290. doi: 10.1021/acs.jmedchem.8b01391. Epub 2019 Jan 18. J Med Chem. 2019. PMID: 30633509 Free article.
Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors.
Romagnoli R, Oliva P, Salvador MK, Camacho ME, Padroni C, Brancale A, Ferla S, Hamel E, Ronca R, Grillo E, Bortolozzi R, Rruga F, Mariotto E, Viola G. Romagnoli R, et al. Among authors: oliva p. Eur J Med Chem. 2019 Nov 1;181:111577. doi: 10.1016/j.ejmech.2019.111577. Epub 2019 Aug 1. Eur J Med Chem. 2019. PMID: 31400707
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
Romagnoli R, Prencipe F, Oliva P, Kimatrai Salvador M, Brancale A, Ferla S, Hamel E, Viola G, Bortolozzi R, Persoons L, Balzarini J, Liekens S, Schols D. Romagnoli R, et al. Among authors: oliva p. Bioorg Chem. 2020 Apr;97:103665. doi: 10.1016/j.bioorg.2020.103665. Epub 2020 Feb 18. Bioorg Chem. 2020. PMID: 32086053 Free article.
243 results