Colas O - Search Results

1

Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates.

Botzanowski T, Erb S, Hernandez-Alba O, Ehkirch A, Colas O, Wagner-Rousset E, Rabuka D, Beck A, Drake PM, Cianférani S. Botzanowski T, et al. Among authors: colas o. MAbs. 2017 Jul;9(5):801-811. doi: 10.1080/19420862.2017.1316914. Epub 2017 Apr 13. MAbs. 2017. PMID: 28406343 Free PMC article.

2

The way forward, enhanced characterization of therapeutic antibody glycosylation: comparison of three level mass spectrometry-based strategies.

Wagner-Rousset E, Bednarczyk A, Bussat MC, Colas O, Corvaïa N, Schaeffer C, Van Dorsselaer A, Beck A. Wagner-Rousset E, et al. Among authors: colas o. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Sep 1;872(1-2):23-37. doi: 10.1016/j.jchromb.2008.03.032. Epub 2008 Apr 15. J Chromatogr B Analyt Technol Biomed Life Sci. 2008. PMID: 18672411

3

Cetuximab Fab and Fc N-glycan fast characterization using IdeS digestion and liquid chromatography coupled to electrospray ionization mass spectrometry.

Janin-Bussat MC, Tonini L, Huillet C, Colas O, Klinguer-Hamour C, Corvaïa N, Beck A. Janin-Bussat MC, et al. Among authors: colas o. Methods Mol Biol. 2013;988:93-113. doi: 10.1007/978-1-62703-327-5_7. Methods Mol Biol. 2013. PMID: 23475716

4

Time resolved native ion-mobility mass spectrometry to monitor dynamics of IgG4 Fab arm exchange and "bispecific" monoclonal antibody formation.

Debaene F, Wagner-Rousset E, Colas O, Ayoub D, Corvaïa N, Van Dorsselaer A, Beck A, Cianférani S. Debaene F, et al. Among authors: colas o. Anal Chem. 2013 Oct 15;85(20):9785-92. doi: 10.1021/ac402237v. Epub 2013 Sep 26. Anal Chem. 2013. PMID: 24007193

5

Antibody-drug conjugate model fast characterization by LC-MS following IdeS proteolytic digestion.

Wagner-Rousset E, Janin-Bussat MC, Colas O, Excoffier M, Ayoub D, Haeuw JF, Rilatt I, Perez M, Corvaïa N, Beck A. Wagner-Rousset E, et al. Among authors: colas o. MAbs. 2014 Jan-Feb;6(1):273-85. doi: 10.4161/mabs.26773. MAbs. 2014. PMID: 24135617 Free PMC article.

6

Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.

Debaene F, Boeuf A, Wagner-Rousset E, Colas O, Ayoub D, Corvaïa N, Van Dorsselaer A, Beck A, Cianférani S. Debaene F, et al. Among authors: colas o. Anal Chem. 2014 Nov 4;86(21):10674-83. doi: 10.1021/ac502593n. Epub 2014 Oct 21. Anal Chem. 2014. PMID: 25270580

7

Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate.

Marcoux J, Champion T, Colas O, Wagner-Rousset E, Corvaïa N, Van Dorsselaer A, Beck A, Cianférani S. Marcoux J, et al. Among authors: colas o. Protein Sci. 2015 Aug;24(8):1210-23. doi: 10.1002/pro.2666. Epub 2015 Mar 31. Protein Sci. 2015. PMID: 25694334 Free PMC article.

8

Characterization of the N-terminal heterogeneities of monoclonal antibodies using in-gel charge derivatization of α-amines and LC-MS/MS.

Ayoub D, Bertaccini D, Diemer H, Wagner-Rousset E, Colas O, Cianférani S, Van Dorsselaer A, Beck A, Schaeffer-Reiss C. Ayoub D, et al. Among authors: colas o. Anal Chem. 2015 Apr 7;87(7):3784-90. doi: 10.1021/ac504427k. Epub 2015 Mar 26. Anal Chem. 2015. PMID: 25769014

9

Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies.

Beck A, Debaene F, Diemer H, Wagner-Rousset E, Colas O, Van Dorsselaer A, Cianférani S. Beck A, et al. Among authors: colas o. J Mass Spectrom. 2015 Feb;50(2):285-97. doi: 10.1002/jms.3554. J Mass Spectrom. 2015. PMID: 25800010

10

Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.

Beck A, Terral G, Debaene F, Wagner-Rousset E, Marcoux J, Janin-Bussat MC, Colas O, Van Dorsselaer A, Cianférani S. Beck A, et al. Among authors: colas o. Expert Rev Proteomics. 2016;13(2):157-83. doi: 10.1586/14789450.2016.1132167. Epub 2016 Jan 22. Expert Rev Proteomics. 2016. PMID: 26653789 Review.

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