Hubbard GB - Search Results

1

IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan.

Ashpole NM, Logan S, Yabluchanskiy A, Mitschelen MC, Yan H, Farley JA, Hodges EL, Ungvari Z, Csiszar A, Chen S, Georgescu C, Hubbard GB, Ikeno Y, Sonntag WE. Ashpole NM, et al. Among authors: hubbard gb. Geroscience. 2017 Apr;39(2):129-145. doi: 10.1007/s11357-017-9971-0. Epub 2017 Apr 13. Geroscience. 2017. PMID: 28409331 Free PMC article.

2

Thioredoxin overexpression in both the cytosol and mitochondria accelerates age-related disease and shortens lifespan in male C57BL/6 mice.

Cunningham GM, Flores LC, Roman MG, Cheng C, Dube S, Allen C, Valentine JM, Hubbard GB, Bai Y, Saunders TL, Ikeno Y. Cunningham GM, et al. Among authors: hubbard gb. Geroscience. 2018 Dec;40(5-6):453-468. doi: 10.1007/s11357-018-0039-6. Epub 2018 Aug 18. Geroscience. 2018. PMID: 30121784 Free PMC article.

3

San Antonio Nathan Shock Center: your one-stop shop for aging research.

Salmon AB, Nelson JF, Gelfond JAL, Javors M, Ginsburg B, Lopez-Cruzan M, Galvan V, Fernandez E, Musi N, Ikeno Y, Hubbard G, Lechleiter J, Hornsby PJ, Strong R. Salmon AB, et al. Geroscience. 2021 Oct;43(5):2105-2118. doi: 10.1007/s11357-021-00417-y. Epub 2021 Jul 9. Geroscience. 2021. PMID: 34240333 Free PMC article.

4

Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice.

Mao K, Quipildor GF, Tabrizian T, Novaj A, Guan F, Walters RO, Delahaye F, Hubbard GB, Ikeno Y, Ejima K, Li P, Allison DB, Salimi-Moosavi H, Beltran PJ, Cohen P, Barzilai N, Huffman DM. Mao K, et al. Among authors: hubbard gb. Nat Commun. 2018 Jun 19;9(1):2394. doi: 10.1038/s41467-018-04805-5. Nat Commun. 2018. PMID: 29921922 Free PMC article.

5

Extension of longevity and reduction of inflammation is ovarian-dependent, but germ cell-independent in post-reproductive female mice.

Habermehl TL, Parkinson KC, Hubbard GB, Ikeno Y, Engelmeyer JI, Schumacher B, Mason JB. Habermehl TL, et al. Among authors: hubbard gb. Geroscience. 2019 Feb;41(1):25-38. doi: 10.1007/s11357-018-0049-4. Epub 2018 Dec 13. Geroscience. 2019. PMID: 30547325 Free PMC article.

6

Does reduced IGF-1R signaling in Igf1r+/- mice alter aging?

Bokov AF, Garg N, Ikeno Y, Thakur S, Musi N, DeFronzo RA, Zhang N, Erickson RC, Gelfond J, Hubbard GB, Adamo ML, Richardson A. Bokov AF, et al. Among authors: hubbard gb. PLoS One. 2011;6(11):e26891. doi: 10.1371/journal.pone.0026891. Epub 2011 Nov 23. PLoS One. 2011. PMID: 22132081 Free PMC article.

7

Reduced incidence and delayed occurrence of fatal neoplastic diseases in growth hormone receptor/binding protein knockout mice.

Ikeno Y, Hubbard GB, Lee S, Cortez LA, Lew CM, Webb CR, Berryman DE, List EO, Kopchick JJ, Bartke A. Ikeno Y, et al. Among authors: hubbard gb. J Gerontol A Biol Sci Med Sci. 2009 May;64(5):522-9. doi: 10.1093/gerona/glp017. Epub 2009 Feb 19. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19228785 Free PMC article.

8

Do Ames dwarf and calorie-restricted mice share common effects on age-related pathology?

Ikeno Y, Hubbard GB, Lee S, Dube SM, Flores LC, Roman MG, Bartke A. Ikeno Y, et al. Among authors: hubbard gb. Pathobiol Aging Age Relat Dis. 2013 Jun 20;3. doi: 10.3402/pba.v3i0.20833. Print 2013. Pathobiol Aging Age Relat Dis. 2013. PMID: 23799173 Free PMC article.

9

Delayed occurrence of fatal neoplastic diseases in ames dwarf mice: correlation to extended longevity.

Ikeno Y, Bronson RT, Hubbard GB, Lee S, Bartke A. Ikeno Y, et al. Among authors: hubbard gb. J Gerontol A Biol Sci Med Sci. 2003 Apr;58(4):291-6. doi: 10.1093/gerona/58.4.b291. J Gerontol A Biol Sci Med Sci. 2003. PMID: 12663691

10

Housing density does not influence the longevity effect of calorie restriction.

Ikeno Y, Hubbard GB, Lee S, Richardson A, Strong R, Diaz V, Nelson JF. Ikeno Y, et al. Among authors: hubbard gb. J Gerontol A Biol Sci Med Sci. 2005 Dec;60(12):1510-7. doi: 10.1093/gerona/60.12.1510. J Gerontol A Biol Sci Med Sci. 2005. PMID: 16424282

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