Wang HY - Search Results

1

Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf^V600E inhibitors.

Wang GM, Wang X, Zhu JM, Guo BB, Yang Z, Xu ZJ, Li B, Wang HY, Meng LH, Zhu WL, Ding J. Wang GM, et al. Among authors: wang x, wang hy. Acta Pharmacol Sin. 2017 Jul;38(7):1059-1068. doi: 10.1038/aps.2016.173. Epub 2017 Apr 17. Acta Pharmacol Sin. 2017. PMID: 28414204 Free PMC article.

2

Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening.

Cai H, Yan G, Zhang X, Gorbenko O, Wang H, Zhu W. Cai H, et al. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3675-9. doi: 10.1016/j.bmcl.2010.04.095. Epub 2010 Apr 24. Bioorg Med Chem Lett. 2010. PMID: 20471252

3

DC260126, a small-molecule antagonist of GPR40, improves insulin tolerance but not glucose tolerance in obese Zucker rats.

Zhang X, Yan G, Li Y, Zhu W, Wang H. Zhang X, et al. Biomed Pharmacother. 2010 Nov;64(9):647-51. doi: 10.1016/j.biopha.2010.06.008. Biomed Pharmacother. 2010. PMID: 20888730

4

Pharmacological inhibition of diacylglycerol acyltransferase 1 reduces body weight gain, hyperlipidemia, and hepatic steatosis in db/db mice.

Zhang XD, Yan JW, Yan GR, Sun XY, Ji J, Li YM, Hu YH, Wang HY. Zhang XD, et al. Among authors: wang hy. Acta Pharmacol Sin. 2010 Nov;31(11):1470-7. doi: 10.1038/aps.2010.104. Acta Pharmacol Sin. 2010. PMID: 21052084 Free PMC article.

5

Computational screening for active compounds targeting protein sequences: methodology and experimental validation.

Wang F, Liu D, Wang H, Luo C, Zheng M, Liu H, Zhu W, Luo X, Zhang J, Jiang H. Wang F, et al. J Chem Inf Model. 2011 Nov 28;51(11):2821-8. doi: 10.1021/ci200264h. Epub 2011 Oct 11. J Chem Inf Model. 2011. PMID: 21955088

6

Classification of 5-HT(1A) receptor agonists and antagonists using GA-SVM method.

Zhu XL, Cai HY, Xu ZJ, Wang Y, Wang HY, Zhang A, Zhu WL. Zhu XL, et al. Among authors: wang y, wang hy. Acta Pharmacol Sin. 2011 Nov;32(11):1424-30. doi: 10.1038/aps.2011.112. Epub 2011 Oct 3. Acta Pharmacol Sin. 2011. PMID: 21963891 Free PMC article.

7

Inhibition of GPR40 protects MIN6 β cells from palmitate-induced ER stress and apoptosis.

Wu J, Sun P, Zhang X, Liu H, Jiang H, Zhu W, Wang H. Wu J, et al. J Cell Biochem. 2012 Apr;113(4):1152-8. doi: 10.1002/jcb.23450. J Cell Biochem. 2012. PMID: 22275065

8

The essential role for aromatic cluster in the β3 adrenergic receptor.

Cai HY, Xu ZJ, Tang J, Sun Y, Chen KX, Wang HY, Zhu WL. Cai HY, et al. Among authors: wang hy. Acta Pharmacol Sin. 2012 Aug;33(8):1062-8. doi: 10.1038/aps.2012.55. Epub 2012 Jun 25. Acta Pharmacol Sin. 2012. PMID: 22728712 Free PMC article.

9

Combining pharmacophore, docking and substructure search approaches to identify and optimize novel B-RafV600E inhibitors.

Xu Z, Yan G, Wang G, Li B, Zhu J, Sun P, Zhang X, Luo C, Wang H, Zhu W. Xu Z, et al. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5428-37. doi: 10.1016/j.bmcl.2012.07.039. Epub 2012 Jul 17. Bioorg Med Chem Lett. 2012. PMID: 22858139

10

[Progress of anti-tumor study based on BRAF].

Yan GR, Xu ZJ, Wang HY, Zhu WL. Yan GR, et al. Among authors: wang hy. Yao Xue Xue Bao. 2012 Dec;47(12):1567-74. Yao Xue Xue Bao. 2012. PMID: 23460959 Review. Chinese.

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