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Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance.
Lasalle M, Hoguet V, Hennuyer N, Leroux F, Piveteau C, Belloy L, Lestavel S, Vallez E, Dorchies E, Duplan I, Sevin E, Culot M, Gosselet F, Boulahjar R, Herledan A, Staels B, Deprez B, Tailleux A, Charton J. Lasalle M, et al. Among authors: staels b. J Med Chem. 2017 May 25;60(10):4185-4211. doi: 10.1021/acs.jmedchem.6b01873. Epub 2017 May 5. J Med Chem. 2017. PMID: 28414465 Free article.
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.
Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk TH, Grefhorst A, Abdelkarim M, Caron S, Torpier G, Fruchart JC, Gonzalez FJ, Kuipers F, Staels B. Cariou B, et al. Among authors: staels b. J Biol Chem. 2006 Apr 21;281(16):11039-49. doi: 10.1074/jbc.M510258200. Epub 2006 Jan 30. J Biol Chem. 2006. PMID: 16446356 Free article.
Studies towards the conception of new selective PPARbeta/delta ligands.
Basséne CE, Suzenet F, Hennuyer N, Staels B, Caignard DH, Dacquet C, Renard P, Guillaumet G. Basséne CE, et al. Among authors: staels b. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4528-32. doi: 10.1016/j.bmcl.2006.06.028. Epub 2006 Jun 23. Bioorg Med Chem Lett. 2006. PMID: 16797985
805 results