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Current State and New Horizons in Applications of Physiologically Based Biopharmaceutics Modeling (PBBM): A Workshop Report.
Tannergren C, Arora S, Babiskin A, Borges L, Chatterjee P, Cheng YH, Dallmann A, Govada A, Heimbach T, Hingle M, Kollipara S, Kotzagiorgis E, Lindahl A, Mackie C, Malamatari M, Mitra A, Moody R, Pepin X, Polli J, Raines K, Rullo G, Sanghavi M, Savkur R, Singh R, Sjögren E, Suarez-Sharp S, Thomas S, Veerasingham S, Wei K, Wu F, Xu Y, Yoon M, Rege B. Tannergren C, et al. Among authors: sjogren e. Mol Pharm. 2025 Jan 6;22(1):5-27. doi: 10.1021/acs.molpharmaceut.4c01148. Epub 2024 Dec 16. Mol Pharm. 2025. PMID: 39680866 Free PMC article.
Bioavailability of a novel sustained-release pellet formulation of 5-flucytosine in healthy-fed participants for use in patients with cryptococcal meningitis.
Ibnou Zekri Lassout N, Goyal V, Krantz E, Simon F, Neven A, Eriksson J, Saayman A, Satam V, Ruffell C, Victor S, Chenel M, Celebic A, Caplain H, Gillon JY, Deshmukh A, Antarkar A, Sjögren E, Ribeiro I. Ibnou Zekri Lassout N, et al. Among authors: sjogren e. Clin Transl Sci. 2024 Sep;17(9):e13908. doi: 10.1111/cts.13908. Clin Transl Sci. 2024. PMID: 39291723 Free PMC article. Clinical Trial.
PBPK modeling of recombinant factor IX Fc fusion protein (rFIXFc) and rFIX to characterize the binding to type 4 collagen in the extravascular space.
Cloesmeijer ME, Sjögren E, Koopman SF, Lenting PJ, Cnossen MH, Mathôt RAA; OPTI‐CLOT study group and SYMPHONY consortium. Cloesmeijer ME, et al. Among authors: sjogren e. CPT Pharmacometrics Syst Pharmacol. 2024 Oct;13(10):1630-1640. doi: 10.1002/psp4.13159. Epub 2024 Sep 16. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 39285704 Free PMC article.
Physiologically based pharmacokinetics modeling and transporter proteomics to predict systemic and local liver and muscle disposition of statins.
Prieto Garcia L, Vildhede A, Nordell P, Ahlström C, Montaser AB, Terasaki T, Lennernäs H, Sjögren E. Prieto Garcia L, et al. Among authors: sjogren e. CPT Pharmacometrics Syst Pharmacol. 2024 Jun;13(6):1029-1043. doi: 10.1002/psp4.13139. Epub 2024 Apr 4. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38576225 Free PMC article.
200 results