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The afc antifungal activity cluster, which is under tight regulatory control of ShvR, is essential for transition from intracellular persistence of Burkholderia cenocepacia to acute pro-inflammatory infection.
Gomes MC, Tasrini Y, Subramoni S, Agnoli K, Feliciano JR, Eberl L, Sokol P, O'Callaghan D, Vergunst AC. Gomes MC, et al. Among authors: vergunst ac. PLoS Pathog. 2018 Dec 4;14(12):e1007473. doi: 10.1371/journal.ppat.1007473. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30513124 Free PMC article.
Macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation.
Mesureur J, Feliciano JR, Wagner N, Gomes MC, Zhang L, Blanco-Gonzalez M, van der Vaart M, O'Callaghan D, Meijer AH, Vergunst AC. Mesureur J, et al. Among authors: vergunst ac. PLoS Pathog. 2017 Jun 26;13(6):e1006437. doi: 10.1371/journal.ppat.1006437. eCollection 2017 Jun. PLoS Pathog. 2017. PMID: 28651010 Free PMC article.
Macrophages as drivers of an opportunistic infection.
Vergunst AC, Carranza NL, Zhang L, Gomes MC, Tasrini Y, Meijer AH, O'Callaghan D. Vergunst AC, et al. Microb Cell. 2017 Sep 13;4(10):362-364. doi: 10.15698/mic2017.10.595. Microb Cell. 2017. PMID: 29082233 Free PMC article.
38 results