Singha S - Search Results

1

Peptide-MHC-based nanomedicines for autoimmunity function as T-cell receptor microclustering devices.

Singha S, Shao K, Yang Y, Clemente-Casares X, Solé P, Clemente A, Blanco J, Dai Q, Song F, Liu SW, Yamanouchi J, Umeshappa CS, Nanjundappa RH, Detampel P, Amrein M, Fandos C, Tanguay R, Newbigging S, Serra P, Khadra A, Chan WCW, Santamaria P. Singha S, et al. Nat Nanotechnol. 2017 Jul;12(7):701-710. doi: 10.1038/nnano.2017.56. Epub 2017 Apr 24. Nat Nanotechnol. 2017. PMID: 28436959

2

Nanoparticle-based immunotherapy for cancer.

Shao K, Singha S, Clemente-Casares X, Tsai S, Yang Y, Santamaria P. Shao K, et al. Among authors: singha s. ACS Nano. 2015 Jan 27;9(1):16-30. doi: 10.1021/nn5062029. Epub 2014 Dec 23. ACS Nano. 2015. PMID: 25469470 Free article. Review.

3

Expanding antigen-specific regulatory networks to treat autoimmunity.

Clemente-Casares X, Blanco J, Ambalavanan P, Yamanouchi J, Singha S, Fandos C, Tsai S, Wang J, Garabatos N, Izquierdo C, Agrawal S, Keough MB, Yong VW, James E, Moore A, Yang Y, Stratmann T, Serra P, Santamaria P. Clemente-Casares X, et al. Among authors: singha s. Nature. 2016 Feb 25;530(7591):434-40. doi: 10.1038/nature16962. Epub 2016 Feb 17. Nature. 2016. PMID: 26886799

4

Nanoparticles for Immune Stimulation Against Infection, Cancer, and Autoimmunity.

Singha S, Shao K, Ellestad KK, Yang Y, Santamaria P. Singha S, et al. ACS Nano. 2018 Nov 27;12(11):10621-10635. doi: 10.1021/acsnano.8b05950. Epub 2018 Oct 15. ACS Nano. 2018. PMID: 30481968 Review.

5

Suppression of a broad spectrum of liver autoimmune pathologies by single peptide-MHC-based nanomedicines.

Umeshappa CS, Singha S, Blanco J, Shao K, Nanjundappa RH, Yamanouchi J, Parés A, Serra P, Yang Y, Santamaria P. Umeshappa CS, et al. Among authors: singha s. Nat Commun. 2019 May 14;10(1):2150. doi: 10.1038/s41467-019-09893-5. Nat Commun. 2019. PMID: 31089130 Free PMC article.

6

In vivo clearance of nanoparticles by transcytosis across alveolar epithelial cells.

Detampel P, Ganguly A, Tehranian S, Green F, Singha S, Santamaria P, Jeje AA, Cho CS, Petri B, Amrein MW. Detampel P, et al. Among authors: singha s. PLoS One. 2019 Sep 30;14(9):e0223339. doi: 10.1371/journal.pone.0223339. eCollection 2019. PLoS One. 2019. PMID: 31568513 Free PMC article.

7

Increased yields and biological potency of knob-into-hole-based soluble MHC class II molecules.

Serra P, Garabatos N, Singha S, Fandos C, Garnica J, Solé P, Parras D, Yamanouchi J, Blanco J, Tort M, Ortega M, Yang Y, Ellestad KK, Santamaria P. Serra P, et al. Among authors: singha s. Nat Commun. 2019 Oct 29;10(1):4917. doi: 10.1038/s41467-019-12902-2. Nat Commun. 2019. PMID: 31664029 Free PMC article.

8

Ubiquitous antigen-specific T regulatory type 1 cells variably suppress hepatic and extrahepatic autoimmunity.

Umeshappa CS, Mbongue J, Singha S, Mohapatra S, Yamanouchi J, Lee JA, Nanjundappa RH, Shao K, Christen U, Yang Y, Ellestad KK, Santamaria P. Umeshappa CS, et al. Among authors: singha s. J Clin Invest. 2020 Apr 1;130(4):1823-1829. doi: 10.1172/JCI130670. J Clin Invest. 2020. PMID: 32125290 Free PMC article.

9

Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP.

Umeshappa CS, Solé P, Surewaard BGJ, Yamanouchi J, Mohapatra S, Uddin MM, Clarke R, Ortega M, Singha S, Mondal D, Yang Y, Vignali DAA, Serra P, Kubes P, Santamaria P. Umeshappa CS, et al. Among authors: singha s. Cell Rep. 2021 Mar 30;34(13):108919. doi: 10.1016/j.celrep.2021.108919. Cell Rep. 2021. PMID: 33789099 Free article.

10

Extremely short bioavailability and fast pharmacodynamic effects of pMHC-based nanomedicines.

Yang Y, Ellestad KK, Singha S, Uddin MM, Clarke R, Mondal D, Garabatos N, Solé P, Fandos C, Serra P, Santamaria P. Yang Y, et al. Among authors: singha s. J Control Release. 2021 Oct 10;338:557-570. doi: 10.1016/j.jconrel.2021.08.043. Epub 2021 Aug 30. J Control Release. 2021. PMID: 34474072 Free article.

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