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Page 1
Seletalisib: Characterization of a Novel, Potent, and Selective Inhibitor of PI3Kδ.
Allen RA, Brookings DC, Powell MJ, Delgado J, Shuttleworth LK, Merriman M, Fahy IJ, Tewari R, Silva JP, Healy LJ, Davies GCG, Twomey B, Cutler RM, Kotian A, Crosby A, McCluskey G, Watt GF, Payne A. Allen RA, et al. Among authors: delgado j. J Pharmacol Exp Ther. 2017 Jun;361(3):429-440. doi: 10.1124/jpet.116.237347. Epub 2017 Apr 25. J Pharmacol Exp Ther. 2017. PMID: 28442583
Human immunoglobulin E flexes between acutely bent and extended conformations.
Drinkwater N, Cossins B, Keeble AH, Wright M, Cain K, Hailu H, Oxbrow A, Delgado J, Shuttleworth LK, Kao MW, McDonnell JM, Beavil AJ, Henry AJ, Sutton BJ. Drinkwater N, et al. Among authors: delgado j. Nat Struct Mol Biol. 2014 Apr;21(4):397-404. doi: 10.1038/nsmb.2795. Epub 2014 Mar 16. Nat Struct Mol Biol. 2014. PMID: 24632569 Free PMC article.
Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase.
Porter J, Lumb S, Lecomte F, Reuberson J, Foley A, Calmiano M, le Riche K, Edwards H, Delgado J, Franklin RJ, Gascon-Simorte JM, Maloney A, Meier C, Batchelor M. Porter J, et al. Among authors: delgado j. Bioorg Med Chem Lett. 2009 Jan 15;19(2):397-400. doi: 10.1016/j.bmcl.2008.11.062. Epub 2008 Nov 21. Bioorg Med Chem Lett. 2009. PMID: 19059779
Discovery of 4-azaindoles as novel inhibitors of c-Met kinase.
Porter J, Lumb S, Franklin RJ, Gascon-Simorte JM, Calmiano M, Riche KL, Lallemand B, Keyaerts J, Edwards H, Maloney A, Delgado J, King L, Foley A, Lecomte F, Reuberson J, Meier C, Batchelor M. Porter J, et al. Among authors: delgado j. Bioorg Med Chem Lett. 2009 May 15;19(10):2780-4. doi: 10.1016/j.bmcl.2009.03.110. Epub 2009 Mar 27. Bioorg Med Chem Lett. 2009. PMID: 19369077
Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab.
Davies AM, Allan EG, Keeble AH, Delgado J, Cossins BP, Mitropoulou AN, Pang MOY, Ceska T, Beavil AJ, Craggs G, Westwood M, Henry AJ, McDonnell JM, Sutton BJ. Davies AM, et al. Among authors: delgado j. J Biol Chem. 2017 Jun 16;292(24):9975-9987. doi: 10.1074/jbc.M117.776476. Epub 2017 Apr 24. J Biol Chem. 2017. PMID: 28438838 Free PMC article.
The Impact of Postprocedural Anticoagulant Use in Patients Undergoing Woven EndoBridge: A Multicenter Propensity Score-Matched Study.
Musmar B, Salim HA, Roy JM, Adeeb N, Fuleihan AA, Atallah E, Sizdahkhani S, Koduri S, Karadimas S, Baba BE, Howard BM, Grossberg JA, Scott KW, Burkhardt JK, Srinivasan VM, Erazu F, Hanel RA, Amllay A, Matouk C, MacNeil A, Chalouhi N, Gomez-Paz S, Grandhi R, Jaikumar V, Levy E, Siddiqui A, Klaiman M, Delgado J, Hoffman H, Arthur A, Hasan DM, Notarianni C, Cuellar HH, Guthikonda B, Morcos J, Tjoumakaris SI, Gooch MR, Rosenwasser RH, Jabbour P. Musmar B, et al. Among authors: delgado j. Transl Stroke Res. 2024 Dec 24. doi: 10.1007/s12975-024-01320-2. Online ahead of print. Transl Stroke Res. 2024. PMID: 39715904
2,106 results