Bassik MC - Search Results

1

Human pyrimidine nucleotide biosynthesis as a target for antiviral chemotherapy.

Okesli A, Khosla C, Bassik MC. Okesli A, et al. Among authors: bassik mc. Curr Opin Biotechnol. 2017 Dec;48:127-134. doi: 10.1016/j.copbio.2017.03.010. Epub 2017 Apr 27. Curr Opin Biotechnol. 2017. PMID: 28458037 Free PMC article. Review.

2

A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience.

Wang C, Wang B, Pandey T, Long Y, Zhang J, Oh F, Sima J, Guo R, Liu Y, Zhang C, Mukherjee S, Bassik M, Lin W, Deng H, Vale G, McDonald JG, Shen K, Ma DK. Wang C, et al. Nat Commun. 2022 Nov 10;13(1):6805. doi: 10.1038/s41467-022-34450-y. Nat Commun. 2022. PMID: 36357390 Free PMC article.

3

The N⁶-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity.

Yoshinaga M, Han K, Morgens DW, Horii T, Kobayashi R, Tsuruyama T, Hia F, Yasukura S, Kajiya A, Cai T, Cruz PHC, Vandenbon A, Suzuki Y, Kawahara Y, Hatada I, Bassik MC, Takeuchi O. Yoshinaga M, et al. Among authors: bassik mc. Nat Commun. 2022 Oct 28;13(1):6435. doi: 10.1038/s41467-022-34078-y. Nat Commun. 2022. PMID: 36307435 Free PMC article.

4

Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification.

Deans RM, Morgens DW, Ökesli A, Pillay S, Horlbeck MA, Kampmann M, Gilbert LA, Li A, Mateo R, Smith M, Glenn JS, Carette JE, Khosla C, Bassik MC. Deans RM, et al. Among authors: bassik mc. Nat Chem Biol. 2016 May;12(5):361-6. doi: 10.1038/nchembio.2050. Epub 2016 Mar 28. Nat Chem Biol. 2016. PMID: 27018887 Free PMC article.

5

Discovery of small molecule inhibitors of human uridine-cytidine kinase 2 by high-throughput screening.

Okesli-Armlovich A, Gupta A, Jimenez M, Auld D, Liu Q, Bassik MC, Khosla C. Okesli-Armlovich A, et al. Among authors: bassik mc. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2559-2564. doi: 10.1016/j.bmcl.2019.08.010. Epub 2019 Aug 7. Bioorg Med Chem Lett. 2019. PMID: 31420268 Free PMC article.

6

A genome-wide analysis of targets of macrolide antibiotics in mammalian cells.

Gupta A, Ökesli-Armlovich A, Morgens D, Bassik MC, Khosla C. Gupta A, et al. Among authors: bassik mc. J Biol Chem. 2020 Feb 14;295(7):2057-2067. doi: 10.1074/jbc.RA119.010770. Epub 2020 Jan 8. J Biol Chem. 2020. PMID: 31915244 Free PMC article.

7

Enhancing the Antiviral Efficacy of RNA-Dependent RNA Polymerase Inhibition by Combination with Modulators of Pyrimidine Metabolism.

Liu Q, Gupta A, Okesli-Armlovich A, Qiao W, Fischer CR, Smith M, Carette JE, Bassik MC, Khosla C. Liu Q, et al. Among authors: bassik mc. Cell Chem Biol. 2020 Jun 18;27(6):668-677.e9. doi: 10.1016/j.chembiol.2020.05.002. Epub 2020 May 21. Cell Chem Biol. 2020. PMID: 32442424 Free PMC article.

8

Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes.

Morgens DW, Deans RM, Li A, Bassik MC. Morgens DW, et al. Among authors: bassik mc. Nat Biotechnol. 2016 Jun;34(6):634-6. doi: 10.1038/nbt.3567. Epub 2016 May 9. Nat Biotechnol. 2016. PMID: 27159373 Free PMC article.

9

Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens.

Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. Matheny CJ, et al. Among authors: bassik mc. Chem Biol. 2013 Nov 21;20(11):1352-63. doi: 10.1016/j.chembiol.2013.09.014. Epub 2013 Oct 31. Chem Biol. 2013. PMID: 24183972 Free PMC article.

10

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

Han K, Jeng EE, Hess GT, Morgens DW, Li A, Bassik MC. Han K, et al. Among authors: bassik mc. Nat Biotechnol. 2017 May;35(5):463-474. doi: 10.1038/nbt.3834. Epub 2017 Mar 20. Nat Biotechnol. 2017. PMID: 28319085 Free PMC article.

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