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Defining an olfactory receptor function in airway smooth muscle cells.
Aisenberg WH, Huang J, Zhu W, Rajkumar P, Cruz R, Santhanam L, Natarajan N, Yong HM, De Santiago B, Oh JJ, Yoon AR, Panettieri RA, Homann O, Sullivan JK, Liggett SB, Pluznick JL, An SS. Aisenberg WH, et al. Among authors: an ss. Sci Rep. 2016 Dec 1;6:38231. doi: 10.1038/srep38231. Sci Rep. 2016. PMID: 27905542 Free PMC article.
Gα12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner.
Yoo EJ, Cao G, Koziol-White CJ, Ojiaku CA, Sunder K, Jude JA, Michael JV, Lam H, Pushkarsky I, Damoiseaux R, Di Carlo D, Ahn K, An SS, Penn RB, Panettieri RA Jr. Yoo EJ, et al. Among authors: an ss. Br J Pharmacol. 2017 Dec;174(23):4383-4395. doi: 10.1111/bph.14040. Epub 2017 Nov 12. Br J Pharmacol. 2017. PMID: 28921504 Free PMC article.
Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines.
Pera T, Deshpande DA, Ippolito M, Wang B, Gavrila A, Michael JV, Nayak AP, Tompkins E, Farrell E, Kroeze WK, Roth BL, Panettieri RA Jr, Benovic JL, An SS, Dulin NO, Penn RB. Pera T, et al. Among authors: an ss. FASEB J. 2018 Feb;32(2):862-874. doi: 10.1096/fj.201700555R. Epub 2018 Jan 4. FASEB J. 2018. PMID: 29042451 Free PMC article.
The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR.
Huang J, Lam H, Koziol-White C, Limjunyawong N, Kim D, Kim N, Karmacharya N, Rajkumar P, Firer D, Dalesio NM, Jude J, Kurten RC, Pluznick JL, Deshpande DA, Penn RB, Liggett SB, Panettieri RA Jr, Dong X, An SS. Huang J, et al. Among authors: an ss. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28485-28495. doi: 10.1073/pnas.2003111117. Epub 2020 Oct 23. Proc Natl Acad Sci U S A. 2020. PMID: 33097666 Free PMC article.
374 results