Urick AK - Search Results

1

Paramagnetic relaxation enhancement for protein-observed ¹⁹F NMR as an enabling approach for efficient fragment screening.

Hawk LML, Gee CT, Urick AK, Hu H, Pomerantz WCK. Hawk LML, et al. Among authors: urick ak. RSC Adv. 2016;6(98):95715-95721. doi: 10.1039/C6RA21226C. Epub 2016 Sep 29. RSC Adv. 2016. PMID: 28496971 Free PMC article.

2

Protein-observed (19)F-NMR for fragment screening, affinity quantification and druggability assessment.

Gee CT, Arntson KE, Urick AK, Mishra NK, Hawk LM, Wisniewski AJ, Pomerantz WC. Gee CT, et al. Among authors: urick ak. Nat Protoc. 2016 Aug;11(8):1414-27. doi: 10.1038/nprot.2016.079. Epub 2016 Jul 14. Nat Protoc. 2016. PMID: 27414758 Free PMC article.

3

Protein-Observed Fluorine NMR Is a Complementary Ligand Discovery Method to ¹H CPMG Ligand-Observed NMR.

Urick AK, Calle LP, Espinosa JF, Hu H, Pomerantz WC. Urick AK, et al. ACS Chem Biol. 2016 Nov 18;11(11):3154-3164. doi: 10.1021/acschembio.6b00730. Epub 2016 Oct 5. ACS Chem Biol. 2016. PMID: 27627661 Free PMC article.

4

Fluorinated aromatic amino acids are sensitive 19F NMR probes for bromodomain-ligand interactions.

Mishra NK, Urick AK, Ember SW, Schönbrunn E, Pomerantz WC. Mishra NK, et al. Among authors: urick ak. ACS Chem Biol. 2014 Dec 19;9(12):2755-60. doi: 10.1021/cb5007344. Epub 2014 Oct 27. ACS Chem Biol. 2014. PMID: 25290579 Free PMC article.

5

Dual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe Molecules.

Urick AK, Hawk LM, Cassel MK, Mishra NK, Liu S, Adhikari N, Zhang W, dos Santos CO, Hall JL, Pomerantz WC. Urick AK, et al. ACS Chem Biol. 2015 Oct 16;10(10):2246-56. doi: 10.1021/acschembio.5b00483. Epub 2015 Jul 28. ACS Chem Biol. 2015. PMID: 26158404 Free PMC article.

6

Prediction of (19)F NMR Chemical Shifts in Labeled Proteins: Computational Protocol and Case Study.

Isley WC 3rd, Urick AK, Pomerantz WC, Cramer CJ. Isley WC 3rd, et al. Among authors: urick ak. Mol Pharm. 2016 Jul 5;13(7):2376-86. doi: 10.1021/acs.molpharmaceut.6b00137. Epub 2016 Jun 2. Mol Pharm. 2016. PMID: 27218275

7

Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor.

Kirberger SE, Ycas PD, Johnson JA, Chen C, Ciccone MF, Woo RWL, Urick AK, Zahid H, Shi K, Aihara H, McAllister SD, Kashani-Sabet M, Shi J, Dickson A, Dos Santos CO, Pomerantz WCK. Kirberger SE, et al. Among authors: urick ak. Org Biomol Chem. 2019 Feb 13;17(7):2020-2027. doi: 10.1039/c8ob02599a. Org Biomol Chem. 2019. PMID: 30706071 Free PMC article.

8

Correction to Letter: Fluorinated Aromatic Amino Acids Are Sensitive (19)F NMR Probes for Bromodomain-Ligand Interactions.

Mishra NK, Urick AK, Ember SW, Schönbrunn E, Pomerantz WC. Mishra NK, et al. Among authors: urick ak. ACS Chem Biol. 2016 Apr 15;11(4):1149. doi: 10.1021/acschembio.6b00049. Epub 2016 Feb 2. ACS Chem Biol. 2016. PMID: 26836633 Free PMC article. No abstract available.

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