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Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW. Huttlin EL, et al. Among authors: li k. Nature. 2017 May 25;545(7655):505-509. doi: 10.1038/nature22366. Epub 2017 May 17. Nature. 2017. PMID: 28514442 Free PMC article.
Next-generation Drosophila protein interactome map and its functional implications.
Bhat G, Li K, Locke G, Theodorou M, Kilambi K, Hori K, Ho D, Obar R, Williams L, Parzen H, Dephoure N, Braun C, Muskavitch M, Celniker SE, Gygi S, Artavanis-Tsakonas S. Bhat G, et al. Among authors: li k. Dev Cell. 2024 Sep 23;59(18):2506-2517.e6. doi: 10.1016/j.devcel.2024.06.002. Epub 2024 Jun 28. Dev Cell. 2024. PMID: 38944040
Genetic map of regional sulcal morphology in the human brain from UK biobank data.
Sun BB, Loomis SJ, Pizzagalli F, Shatokhina N, Painter JN, Foley CN; Biogen Biobank Team; Jensen ME, McLaren DG, Chintapalli SS, Zhu AH, Dixon D, Islam T, Ba Gari I, Runz H, Medland SE, Thompson PM, Jahanshad N, Whelan CD. Sun BB, et al. Nat Commun. 2022 Oct 14;13(1):6071. doi: 10.1038/s41467-022-33829-1. Nat Commun. 2022. PMID: 36241887 Free PMC article.
Rare genetic variants impact muscle strength.
Huang Y, Bodnar D, Chen CY, Sanchez-Andrade G, Sanderson M; Biogen Biobank Team; Shi J, Meilleur KG, Hurles ME, Gerety SS, Tsai EA, Runz H. Huang Y, et al. Nat Commun. 2023 Jun 10;14(1):3449. doi: 10.1038/s41467-023-39247-1. Nat Commun. 2023. PMID: 37301943 Free PMC article.
CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling.
Henry KL, Kellner D, Bajrami B, Anderson JE, Beyna M, Bhisetti G, Cameron T, Capacci AG, Bertolotti-Ciarlet A, Feng J, Gao B, Hopkins B, Jenkins T, Li K, May-Dracka T, Murugan P, Wei R, Zeng W, Allaire N, Buckler A, Loh C, Juhasz P, Lucas B, Ennis KA, Vollman E, Cahir-McFarland E, Hett EC, Ols ML. Henry KL, et al. Among authors: li k. Sci Signal. 2018 Jul 31;11(541):eaam8216. doi: 10.1126/scisignal.aam8216. Sci Signal. 2018. PMID: 30065029
A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay.
Bray MA, Gustafsdottir SM, Rohban MH, Singh S, Ljosa V, Sokolnicki KL, Bittker JA, Bodycombe NE, Dancík V, Hasaka TP, Hon CS, Kemp MM, Li K, Walpita D, Wawer MJ, Golub TR, Schreiber SL, Clemons PA, Shamji AF, Carpenter AE. Bray MA, et al. Among authors: li k. Gigascience. 2017 Dec 1;6(12):1-5. doi: 10.1093/gigascience/giw014. Gigascience. 2017. PMID: 28327978 Free PMC article.
An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2.
Connor-Robson N, Booth H, Martin JG, Gao B, Li K, Doig N, Vowles J, Browne C, Klinger L, Juhasz P, Klein C, Cowley SA, Bolam P, Hirst W, Wade-Martins R. Connor-Robson N, et al. Among authors: li k. Neurobiol Dis. 2019 Jul;127:512-526. doi: 10.1016/j.nbd.2019.04.005. Epub 2019 Apr 5. Neurobiol Dis. 2019. PMID: 30954703 Free PMC article.
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