Fenton AW - Search Results

1

A bioenergetics systems evaluation of ketogenic diet liver effects.

Hutfles LJ, Wilkins HM, Koppel SJ, Weidling IW, Selfridge JE, Tan E, Thyfault JP, Slawson C, Fenton AW, Zhu H, Swerdlow RH. Hutfles LJ, et al. Among authors: fenton aw. Appl Physiol Nutr Metab. 2017 Sep;42(9):955-962. doi: 10.1139/apnm-2017-0068. Epub 2017 May 17. Appl Physiol Nutr Metab. 2017. PMID: 28514599 Free PMC article.

2

Mutational mimics of allosteric effectors: a genome editing design to validate allosteric drug targets.

Tang Q, Villar MT, Artigues A, Thyfault JP, Apte U, Zhu H, Peterson KR, Fenton AW. Tang Q, et al. Among authors: fenton aw. Sci Rep. 2019 Jun 21;9(1):9031. doi: 10.1038/s41598-019-45202-2. Sci Rep. 2019. PMID: 31227746 Free PMC article.

3

The N-terminal intrinsically disordered region of Ncb5or docks with the cytochrome b₅ core to form a helical motif that is of ancient origin.

Benson DR, Deng B, Kashipathy MM, Lovell S, Battaile KP, Cooper A, Gao P, Fenton AW, Zhu H. Benson DR, et al. Among authors: fenton aw. Proteins. 2024 Apr;92(4):554-566. doi: 10.1002/prot.26647. Epub 2023 Dec 1. Proteins. 2024. PMID: 38041394 Free PMC article.

4

Allosteric regulation of human liver pyruvate kinase by peptides that mimic the phosphorylated/dephosphorylated N-terminus.

Prasannan CB, Tang Q, Fenton AW. Prasannan CB, et al. Among authors: fenton aw. Methods Mol Biol. 2012;796:335-49. doi: 10.1007/978-1-61779-334-9_18. Methods Mol Biol. 2012. PMID: 22052499 Free PMC article.

5

An activating interaction between the unphosphorylated n-terminus of human liver pyruvate kinase and the main body of the protein is interrupted by phosphorylation.

Fenton AW, Tang Q. Fenton AW, et al. Biochemistry. 2009 May 12;48(18):3816-8. doi: 10.1021/bi900421f. Biochemistry. 2009. PMID: 19320443 Free PMC article.

6

Energetic coupling between an oxidizable cysteine and the phosphorylatable N-terminus of human liver pyruvate kinase.

Holyoak T, Zhang B, Deng J, Tang Q, Prasannan CB, Fenton AW. Holyoak T, et al. Among authors: fenton aw. Biochemistry. 2013 Jan 22;52(3):466-76. doi: 10.1021/bi301341r. Epub 2013 Jan 11. Biochemistry. 2013. PMID: 23270483 Free PMC article.

7

Identification of biochemically neutral positions in liver pyruvate kinase.

Martin TA, Wu T, Tang Q, Dougherty LL, Parente DJ, Swint-Kruse L, Fenton AW. Martin TA, et al. Among authors: fenton aw. Proteins. 2020 Oct;88(10):1340-1350. doi: 10.1002/prot.25953. Epub 2020 Jun 27. Proteins. 2020. PMID: 32449829 Free PMC article.

8

The phosphate moiety of phosphoenolpyruvate does NOT contribute to allosteric regulation of liver pyruvate kinase by fructose-1,6-bisphosphate^✝.

Chappell BM, Fenton AW. Chappell BM, et al. Among authors: fenton aw. Arch Biochem Biophys. 2020 Nov 30;695:108633. doi: 10.1016/j.abb.2020.108633. Epub 2020 Oct 16. Arch Biochem Biophys. 2020. PMID: 33075302 Free PMC article.

9

The pH dependence of the allosteric response of human liver pyruvate kinase to fructose-1,6-bisphosphate, ATP, and alanine.

Fenton AW, Hutchinson M. Fenton AW, et al. Arch Biochem Biophys. 2009 Apr 1;484(1):16-23. doi: 10.1016/j.abb.2009.01.011. Epub 2009 Jan 20. Arch Biochem Biophys. 2009. PMID: 19467627 Free PMC article.

10

The impact of ions on allosteric functions in human liver pyruvate kinase.

Fenton AW, Alontaga AY. Fenton AW, et al. Methods Enzymol. 2009;466:83-107. doi: 10.1016/S0076-6879(09)66005-5. Epub 2009 Nov 13. Methods Enzymol. 2009. PMID: 21609859 Free PMC article.

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