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Page 1
Crystal structure of the Frizzled 4 receptor in a ligand-free state.
Yang S, Wu Y, Xu TH, de Waal PW, He Y, Pu M, Chen Y, DeBruine ZJ, Zhang B, Zaidi SA, Popov P, Guo Y, Han GW, Lu Y, Suino-Powell K, Dong S, Harikumar KG, Miller LJ, Katritch V, Xu HE, Shui W, Stevens RC, Melcher K, Zhao S, Xu F. Yang S, et al. Among authors: debruine zj. Nature. 2018 Aug;560(7720):666-670. doi: 10.1038/s41586-018-0447-x. Epub 2018 Aug 22. Nature. 2018. PMID: 30135577
Independent phenotypic plasticity axes define distinct obesity sub-types.
Yang CH, Fagnocchi L, Apostle S, Wegert V, Casaní-Galdón S, Landgraf K, Panzeri I, Dror E, Heyne S, Wörpel T, Chandler DP, Lu D, Yang T, Gibbons E, Guerreiro R, Bras J, Thomasen M, Grunnet LG, Vaag AA, Gillberg L, Grundberg E, Conesa A, Körner A; PERMUTE; Pospisilik JA. Yang CH, et al. Nat Metab. 2022 Sep;4(9):1150-1165. doi: 10.1038/s42255-022-00629-2. Epub 2022 Sep 12. Nat Metab. 2022. PMID: 36097183 Free PMC article.
CUL5 is required for thalidomide-dependent inhibition of cellular proliferation.
Kunkler B, Salamango D, DeBruine ZJ, Ploch C, Dean S, Grossens D, Hledin MP, Marquez GA, Madden J, Schnell A, Short M, Burnatowska-Hledin MA. Kunkler B, et al. Among authors: debruine zj. PLoS One. 2018 May 10;13(5):e0196760. doi: 10.1371/journal.pone.0196760. eCollection 2018. PLoS One. 2018. PMID: 29746508 Free PMC article.
EZH2-driven immune evasion defines high-risk pediatric AML with t(16;21) FUS::ERG gene fusion.
Buteyn NJ, Burke CG, Sartori VJ, Deering-Gardner E, DeBruine ZJ, Kamarudin D, Chandler DP, Monovich AC, Perez MW, Yi JS, Ries RE, Alonzo TA, Ryan RJ, Meshinchi S, Triche TJ Jr. Buteyn NJ, et al. Among authors: debruine zj. bioRxiv [Preprint]. 2024 Jun 25:2024.05.14.594150. doi: 10.1101/2024.05.14.594150. bioRxiv. 2024. PMID: 38798454 Free PMC article. Preprint.