Cook SJ - Search Results

1

Control of cell death and mitochondrial fission by ERK1/2 MAP kinase signalling.

Cook SJ, Stuart K, Gilley R, Sale MJ. Cook SJ, et al. FEBS J. 2017 Dec;284(24):4177-4195. doi: 10.1111/febs.14122. Epub 2017 Jun 18. FEBS J. 2017. PMID: 28548464 Free PMC article. Review.

2

The duration of ERK1/2 activity determines the activation of c-Fos and Fra-1 and the composition and quantitative transcriptional output of AP-1.

Chalmers CJ, Gilley R, March HN, Balmanno K, Cook SJ. Chalmers CJ, et al. Among authors: cook sj. Cell Signal. 2007 Apr;19(4):695-704. doi: 10.1016/j.cellsig.2006.09.001. Epub 2006 Sep 15. Cell Signal. 2007. PMID: 17052890

3

ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL.

Ewings KE, Hadfield-Moorhouse K, Wiggins CM, Wickenden JA, Balmanno K, Gilley R, Degenhardt K, White E, Cook SJ. Ewings KE, et al. Among authors: cook sj. EMBO J. 2007 Jun 20;26(12):2856-67. doi: 10.1038/sj.emboj.7601723. Epub 2007 May 24. EMBO J. 2007. PMID: 17525735 Free PMC article.

4

Bim and the pro-survival Bcl-2 proteins: opposites attract, ERK repels.

Ewings KE, Wiggins CM, Cook SJ. Ewings KE, et al. Among authors: cook sj. Cell Cycle. 2007 Sep 15;6(18):2236-40. doi: 10.4161/cc.6.18.4728. Epub 2007 Jul 10. Cell Cycle. 2007. PMID: 17881896 Review.

5

c-Cbl is not required for ERK1/2-dependent degradation of BimEL.

Wiggins CM, Band H, Cook SJ. Wiggins CM, et al. Among authors: cook sj. Cell Signal. 2007 Dec;19(12):2605-11. doi: 10.1016/j.cellsig.2007.08.008. Epub 2007 Aug 23. Cell Signal. 2007. PMID: 17884340 Free PMC article.

6

Colorectal cancer cells with the BRAF(V600E) mutation are addicted to the ERK1/2 pathway for growth factor-independent survival and repression of BIM.

Wickenden JA, Jin H, Johnson M, Gillings AS, Newson C, Austin M, Chell SD, Balmanno K, Pritchard CA, Cook SJ. Wickenden JA, et al. Among authors: cook sj. Oncogene. 2008 Dec 4;27(57):7150-61. doi: 10.1038/onc.2008.335. Epub 2008 Sep 22. Oncogene. 2008. PMID: 18806830 Free PMC article.

7

Tumour cell survival signalling by the ERK1/2 pathway.

Balmanno K, Cook SJ. Balmanno K, et al. Among authors: cook sj. Cell Death Differ. 2009 Mar;16(3):368-77. doi: 10.1038/cdd.2008.148. Epub 2008 Oct 10. Cell Death Differ. 2009. PMID: 18846109 Review.

8

ERK1/2, but not ERK5, is necessary and sufficient for phosphorylation and activation of c-Fos.

Gilley R, March HN, Cook SJ. Gilley R, et al. Among authors: cook sj. Cell Signal. 2009 Jun;21(6):969-77. doi: 10.1016/j.cellsig.2009.02.006. Epub 2009 Feb 25. Cell Signal. 2009. PMID: 19249353

9

Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines.

Balmanno K, Chell SD, Gillings AS, Hayat S, Cook SJ. Balmanno K, et al. Among authors: cook sj. Int J Cancer. 2009 Nov 15;125(10):2332-41. doi: 10.1002/ijc.24604. Int J Cancer. 2009. PMID: 19637312

10

Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics.

Gillings AS, Balmanno K, Wiggins CM, Johnson M, Cook SJ. Gillings AS, et al. Among authors: cook sj. FEBS J. 2009 Nov;276(21):6050-62. doi: 10.1111/j.1742-4658.2009.07329.x. Epub 2009 Sep 29. FEBS J. 2009. PMID: 19788418 Free article. Review.

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