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Biallelic TRIP13 mutations predispose to Wilms tumor and chromosome missegregation.
Yost S, de Wolf B, Hanks S, Zachariou A, Marcozzi C, Clarke M, de Voer R, Etemad B, Uijttewaal E, Ramsay E, Wylie H, Elliott A, Picton S, Smith A, Smithson S, Seal S, Ruark E, Houge G, Pines J, Kops GJPL, Rahman N. Yost S, et al. Among authors: kops gjpl. Nat Genet. 2017 Jul;49(7):1148-1151. doi: 10.1038/ng.3883. Epub 2017 May 29. Nat Genet. 2017. PMID: 28553959 Free PMC article.
Targeting the mitotic checkpoint to kill tumor cells.
Janssen A, Kops GJ, Medema RH. Janssen A, et al. Horm Cancer. 2011 Apr;2(2):113-6. doi: 10.1007/s12672-010-0059-x. Epub 2010 Dec 17. Horm Cancer. 2011. PMID: 21475725 Free PMC article.
Sequential cancer mutations in cultured human intestinal stem cells.
Drost J, van Jaarsveld RH, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, Sachs N, Overmeer RM, Offerhaus GJ, Begthel H, Korving J, van de Wetering M, Schwank G, Logtenberg M, Cuppen E, Snippert HJ, Medema JP, Kops GJ, Clevers H. Drost J, et al. Nature. 2015 May 7;521(7550):43-7. doi: 10.1038/nature14415. Epub 2015 Apr 29. Nature. 2015. PMID: 25924068
Kinetochore Malfunction in Human Pathologies.
de Wolf B, Kops GJPL. de Wolf B, et al. Among authors: kops gjpl. Adv Exp Med Biol. 2017;1002:69-91. doi: 10.1007/978-3-319-57127-0_4. Adv Exp Med Biol. 2017. PMID: 28600783 Review.
Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis.
Mur P, De Voer RM, Olivera-Salguero R, Rodríguez-Perales S, Pons T, Setién F, Aiza G, Valdés-Mas R, Bertini A, Pineda M, Vreede L, Navarro M, Iglesias S, González S, Brunet J, Valencia A, Esteller M, Lázaro C, Kops GJPL, Urioste M, Puente XS, Capellá G, Valle L. Mur P, et al. Among authors: kops gjpl. Mol Cancer. 2018 Feb 15;17(1):23. doi: 10.1186/s12943-018-0762-8. Mol Cancer. 2018. PMID: 29448935 Free PMC article.
115 results