Ye L - Search Results

1

Development of a validated UPLC-MS/MS method for determination of humantenmine in rat plasma and its application in pharmacokinetics and bioavailability studies.

Hu Y, Chen M, Wang Z, Lan Y, Tang L, Liu M, Zhao J, Hu M, Zhang L, Ye L. Hu Y, et al. Among authors: ye l. Biomed Chromatogr. 2017 Dec;31(12). doi: 10.1002/bmc.4017. Epub 2017 Jul 3. Biomed Chromatogr. 2017. PMID: 28557019

2

Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.

Tang L, Ye L, Singh R, Wu B, Lv C, Zhao J, Liu Z, Hu M. Tang L, et al. Among authors: ye l. Mol Pharm. 2010 Jun 7;7(3):664-79. doi: 10.1021/mp900223c. Mol Pharm. 2010. PMID: 20297805 Free PMC article.

3

Species and gender differences affect the metabolism of emodin via glucuronidation.

Liu W, Tang L, Ye L, Cai Z, Xia B, Zhang J, Hu M, Liu Z. Liu W, et al. Among authors: ye l. AAPS J. 2010 Sep;12(3):424-36. doi: 10.1208/s12248-010-9200-6. Epub 2010 May 14. AAPS J. 2010. PMID: 20467923 Free PMC article.

4

Characterization of metabolites and human P450 isoforms involved in the microsomal metabolism of mesaconitine.

Ye L, Tang L, Gong Y, Lv C, Zheng Z, Jiang Z, Liu Z. Ye L, et al. Xenobiotica. 2011 Jan;41(1):46-58. doi: 10.3109/00498254.2010.524950. Epub 2010 Nov 24. Xenobiotica. 2011. PMID: 21105783

5

Sensitive and robust UPLC-MS/MS method to determine the gender-dependent pharmacokinetics in rats of emodin and its glucuronide.

Liu W, Zheng Z, Liu X, Gao S, Ye L, Yang Z, Hu M, Liu Z. Liu W, et al. Among authors: ye l. J Pharm Biomed Anal. 2011 Apr 5;54(5):1157-62. doi: 10.1016/j.jpba.2010.12.004. Epub 2010 Dec 9. J Pharm Biomed Anal. 2011. PMID: 21195574 Free PMC article.

6

Involvement of CYP3A4/5 and CYP2D6 in the metabolism of aconitine using human liver microsomes and recombinant CYP450 enzymes.

Tang L, Ye L, Lv C, Zheng Z, Gong Y, Liu Z. Tang L, et al. Among authors: ye l. Toxicol Lett. 2011 Apr 10;202(1):47-54. doi: 10.1016/j.toxlet.2011.01.019. Epub 2011 Jan 28. Toxicol Lett. 2011. PMID: 21277363

7

Microsomal cytochrome P450-mediated metabolism of hypaconitine, an active and highly toxic constituent derived from Aconitum species.

Ye L, Wang T, Yang C, Tang L, Zhou J, Lv C, Gong Y, Jiang Z, Liu Z. Ye L, et al. Toxicol Lett. 2011 Jul 4;204(1):81-91. doi: 10.1016/j.toxlet.2011.04.015. Epub 2011 Apr 27. Toxicol Lett. 2011. PMID: 21550385

8

Sulfation of selected mono-hydroxyflavones by sulfotransferases in vitro: a species and gender comparison.

Yang CH, Tang L, Lv C, Ye L, Xia BJ, Hu M, Liu ZQ. Yang CH, et al. Among authors: ye l. J Pharm Pharmacol. 2011 Jul;63(7):967-70. doi: 10.1111/j.2042-7158.2011.01298.x. J Pharm Pharmacol. 2011. PMID: 21635263 Free PMC article.

9

Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P-glycoprotein.

Ye L, Wang T, Tang L, Liu W, Yang Z, Zhou J, Zheng Z, Cai Z, Hu M, Liu Z. Ye L, et al. J Pharm Sci. 2011 Nov;100(11):5007-17. doi: 10.1002/jps.22693. Epub 2011 Jun 30. J Pharm Sci. 2011. PMID: 21721007

10

Pharmacokinetics of aconitine as the targeted marker of Fuzi (Aconitum carmichaeli) following single and multiple oral administrations of Fuzi extracts in rat by UPLC/MS/MS.

Tang L, Gong Y, Lv C, Ye L, Liu L, Liu Z. Tang L, et al. Among authors: ye l. J Ethnopharmacol. 2012 Jun 1;141(2):736-41. doi: 10.1016/j.jep.2011.08.070. Epub 2011 Sep 8. J Ethnopharmacol. 2012. PMID: 21924342

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