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Designing multitarget anti-inflammatory agents: chemical modulation of the lumiracoxib structure toward dual thromboxane antagonists-COX-2 inhibitors.
Bertinaria M, Shaikh MA, Buccellati C, Cena C, Rolando B, Lazzarato L, Fruttero R, Gasco A, Hoxha M, Capra V, Sala A, Rovati GE. Bertinaria M, et al. Among authors: buccellati c. ChemMedChem. 2012 Sep;7(9):1647-60. doi: 10.1002/cmdc.201200272. Epub 2012 Aug 2. ChemMedChem. 2012. PMID: 22865828 Free article.
A potential role of PUFAs and COXIBs in cancer chemoprevention.
Vara-Messler M, Buccellati C, Pustina L, Folco G, Rovati GE, Hoxha M. Vara-Messler M, et al. Among authors: buccellati c. Prostaglandins Other Lipid Mediat. 2015 Jul;120:97-102. doi: 10.1016/j.prostaglandins.2015.04.003. Epub 2015 Apr 20. Prostaglandins Other Lipid Mediat. 2015. PMID: 25908304 Review.
Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain.
Kramer JS, Woltersdorf S, Duflot T, Hiesinger K, Lillich FF, Knöll F, Wittmann SK, Klingler FM, Brunst S, Chaikuad A, Morisseau C, Hammock BD, Buccellati C, Sala A, Rovati GE, Leuillier M, Fraineau S, Rondeaux J, Hernandez-Olmos V, Heering J, Merk D, Pogoryelov D, Steinhilber D, Knapp S, Bellien J, Proschak E. Kramer JS, et al. Among authors: buccellati c. J Med Chem. 2019 Sep 26;62(18):8443-8460. doi: 10.1021/acs.jmedchem.9b00445. Epub 2019 Sep 17. J Med Chem. 2019. PMID: 31436984 Free PMC article.
Rapid Metabolization of Protectin D1 by β-Oxidation of Its Polar Head Chain.
Balas L, Risé P, Gandrath D, Rovati G, Bolego C, Stellari F, Trenti A, Buccellati C, Durand T, Sala A. Balas L, et al. Among authors: buccellati c. J Med Chem. 2019 Nov 14;62(21):9961-9975. doi: 10.1021/acs.jmedchem.9b01463. Epub 2019 Oct 30. J Med Chem. 2019. PMID: 31626541 Free article.
Pharmacological characterization of 2NTX-99 [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide], a potential antiatherothrombotic agent with antithromboxane and nitric oxide donor activity in platelet and vascular preparations.
Buccellati C, Sala A, Rossoni G, Capra V, Rovati GE, Di Gennaro A, Folco G, Colli S, Casagrande C. Buccellati C, et al. J Pharmacol Exp Ther. 2006 May;317(2):830-7. doi: 10.1124/jpet.105.097170. Epub 2006 Jan 6. J Pharmacol Exp Ther. 2006. PMID: 16399881
44 results