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MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation.
Cell Death Differ. 2017 Sep;24(9):1564-1576. doi: 10.1038/cdd.2017.79. Epub 2017 Jun 2.
Cell Death Differ. 2017.
PMID: 28574509
Free PMC article.
eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response.
Jan A, Jansonius B, Delaidelli A, Somasekharan SP, Bhanshali F, Vandal M, Negri GL, Moerman D, MacKenzie I, Calon F, Hayden MR, Taubert S, Sorensen PH.
Jan A, et al. Among authors: jansonius b.
Acta Neuropathol. 2017 Jan;133(1):101-119. doi: 10.1007/s00401-016-1634-1. Epub 2016 Oct 17.
Acta Neuropathol. 2017.
PMID: 27752775
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Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity.
Jan A, Jansonius B, Delaidelli A, Bhanshali F, An YA, Ferreira N, Smits LM, Negri GL, Schwamborn JC, Jensen PH, Mackenzie IR, Taubert S, Sorensen PH.
Jan A, et al. Among authors: jansonius b.
Acta Neuropathol Commun. 2018 Jul 2;6(1):54. doi: 10.1186/s40478-018-0554-9.
Acta Neuropathol Commun. 2018.
PMID: 29961428
Free PMC article.
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