Brüning JC - Search Results

1

Insulin controls food intake and energy balance via NPY neurons.

Loh K, Zhang L, Brandon A, Wang Q, Begg D, Qi Y, Fu M, Kulkarni R, Teo J, Baldock P, Brüning JC, Cooney G, Neely GG, Herzog H. Loh K, et al. Among authors: bruning jc. Mol Metab. 2017 Apr 12;6(6):574-584. doi: 10.1016/j.molmet.2017.03.013. eCollection 2017 Jun. Mol Metab. 2017. PMID: 28580287 Free PMC article.

2

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

Kulkarni RN, Brüning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. Kulkarni RN, et al. Among authors: bruning jc. Cell. 1999 Feb 5;96(3):329-39. doi: 10.1016/s0092-8674(00)80546-2. Cell. 1999. PMID: 10025399 Free article.

3

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.

Kulkarni RN, Winnay JN, Daniels M, Brüning JC, Flier SN, Hanahan D, Kahn CR. Kulkarni RN, et al. Among authors: bruning jc. J Clin Invest. 1999 Dec;104(12):R69-75. doi: 10.1172/JCI8339. J Clin Invest. 1999. PMID: 10606633 Free PMC article.

4

Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes mellitus.

Kahn CR, Brüning JC, Michael MD, Kulkarni RN. Kahn CR, et al. Among authors: bruning jc. J Pediatr Endocrinol Metab. 2000;13 Suppl 6:1377-84. doi: 10.1515/jpem-2000-s611. J Pediatr Endocrinol Metab. 2000. PMID: 11202213 Review.

5

The role of insulin receptor signaling in the brain.

Plum L, Schubert M, Brüning JC. Plum L, et al. Among authors: bruning jc. Trends Endocrinol Metab. 2005 Mar;16(2):59-65. doi: 10.1016/j.tem.2005.01.008. Trends Endocrinol Metab. 2005. PMID: 15734146 Review.

6

Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.

Baumgartl J, Baudler S, Scherner M, Babaev V, Makowski L, Suttles J, McDuffie M, Tobe K, Kadowaki T, Fazio S, Kahn CR, Hotamisligil GS, Krone W, Linton M, Brüning JC. Baumgartl J, et al. Among authors: bruning jc. Cell Metab. 2006 Apr;3(4):247-56. doi: 10.1016/j.cmet.2006.02.010. Cell Metab. 2006. PMID: 16581002 Free PMC article.

7

Central insulin action in energy and glucose homeostasis.

Plum L, Belgardt BF, Brüning JC. Plum L, et al. Among authors: bruning jc. J Clin Invest. 2006 Jul;116(7):1761-6. doi: 10.1172/JCI29063. J Clin Invest. 2006. PMID: 16823473 Free PMC article. Review.

8

Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.

Könner AC, Janoschek R, Plum L, Jordan SD, Rother E, Ma X, Xu C, Enriori P, Hampel B, Barsh GS, Kahn CR, Cowley MA, Ashcroft FM, Brüning JC. Könner AC, et al. Among authors: bruning jc. Cell Metab. 2007 Jun;5(6):438-49. doi: 10.1016/j.cmet.2007.05.004. Cell Metab. 2007. PMID: 17550779 Free article.

9

Activation of Stat3 signaling in AgRP neurons promotes locomotor activity.

Mesaros A, Koralov SB, Rother E, Wunderlich FT, Ernst MB, Barsh GS, Rajewsky K, Brüning JC. Mesaros A, et al. Among authors: bruning jc. Cell Metab. 2008 Mar;7(3):236-48. doi: 10.1016/j.cmet.2008.01.007. Cell Metab. 2008. PMID: 18316029 Free article.

10

PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response.

Belgardt BF, Husch A, Rother E, Ernst MB, Wunderlich FT, Hampel B, Klöckener T, Alessi D, Kloppenburg P, Brüning JC. Belgardt BF, et al. Among authors: bruning jc. Cell Metab. 2008 Apr;7(4):291-301. doi: 10.1016/j.cmet.2008.01.006. Cell Metab. 2008. PMID: 18396135 Free article.

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