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The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis.
Janes J, Young ME, Chen E, Rogers NH, Burgstaller-Muehlbacher S, Hughes LD, Love MS, Hull MV, Kuhen KL, Woods AK, Joseph SB, Petrassi HM, McNamara CW, Tremblay MS, Su AI, Schultz PG, Chatterjee AK. Janes J, et al. Among authors: chen e. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10750-10755. doi: 10.1073/pnas.1810137115. Epub 2018 Oct 3. Proc Natl Acad Sci U S A. 2018. PMID: 30282735 Free PMC article.
Small-Molecule Stimulators of NRF1 Transcriptional Activity.
Iaconelli J, Ibrahim L, Chen E, Hull M, Schultz PG, Bollong MJ. Iaconelli J, et al. Among authors: chen e. Chembiochem. 2020 Jul 1;21(13):1816-1819. doi: 10.1002/cbic.201900487. Epub 2019 Nov 8. Chembiochem. 2020. PMID: 31596542
Cell-Based Ligand Discovery for the ENL YEATS Domain.
Asiaban JN, Milosevich N, Chen E, Bishop TR, Wang J, Zhang Y, Ackerman CJ, Hampton EN, Young TS, Hull MV, Cravatt BF, Erb MA. Asiaban JN, et al. Among authors: chen e. ACS Chem Biol. 2020 Apr 17;15(4):895-903. doi: 10.1021/acschembio.0c00124. Epub 2020 Mar 19. ACS Chem Biol. 2020. PMID: 32176478 Free PMC article.
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry.
Kitamura S, Zheng Q, Woehl JL, Solania A, Chen E, Dillon N, Hull MV, Kotaniguchi M, Cappiello JR, Kitamura S, Nizet V, Sharpless KB, Wolan DW. Kitamura S, et al. Among authors: chen e. J Am Chem Soc. 2020 Jun 24;142(25):10899-10904. doi: 10.1021/jacs.9b13652. Epub 2020 Jun 10. J Am Chem Soc. 2020. PMID: 32479075 Free PMC article.
High-Throughput Screening for Drugs That Inhibit Papain-Like Protease in SARS-CoV-2.
Smith E, Davis-Gardner ME, Garcia-Ordonez RD, Nguyen TT, Hull M, Chen E, Baillargeon P, Scampavia L, Strutzenberg T, Griffin PR, Farzan M, Spicer TP. Smith E, et al. Among authors: chen e. SLAS Discov. 2020 Dec;25(10):1152-1161. doi: 10.1177/2472555220963667. Epub 2020 Oct 10. SLAS Discov. 2020. PMID: 33043784 Free PMC article.
6,169 results