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Development and validation of a bioanalytical method based on LC-MS/MS analysis for the quantitation of CIGB-814 peptide in plasma from Rheumatoid Arthritis patients.
Cabrales-Rico A, Ramos Y, Besada V, Del Carmen Domínguez M, Lorenzo N, García O, Alexis J, Prada D, Reyes Y, López AM, Masforrol Y, Garay H, González LJ. Cabrales-Rico A, et al. Among authors: del carmen dominguez m. J Pharm Biomed Anal. 2017 Sep 5;143:130-140. doi: 10.1016/j.jpba.2017.05.030. Epub 2017 Jun 1. J Pharm Biomed Anal. 2017. PMID: 28595106
APL1, an altered peptide ligand derived from human heat-shock protein 60, increases the frequency of Tregs and its suppressive capacity against antigen responding effector CD4 + T cells from rheumatoid arthritis patients.
Barberá A, Lorenzo N, van Kooten P, van Roon J, de Jager W, Prada D, Gómez J, Padrón G, van Eden W, Broere F, Del Carmen Domínguez M. Barberá A, et al. Among authors: del carmen dominguez m. Cell Stress Chaperones. 2016 Jul;21(4):735-44. doi: 10.1007/s12192-016-0698-0. Epub 2016 May 30. Cell Stress Chaperones. 2016. PMID: 27241313 Free PMC article.
APL-2, an altered peptide ligand derived from heat-shock protein 60, induces interleukin-10 in peripheral blood mononuclear cell derived from juvenile idiopathic arthritis patients and downregulates the inflammatory response in collagen-induced arthritis model.
Lorenzo N, Cantera D, Barberá A, Alonso A, Chall E, Franco L, Ancizar J, Nuñez Y, Altruda F, Silengo L, Padrón G, Del Carmen Dominguez M. Lorenzo N, et al. Among authors: del carmen dominguez m. Clin Exp Med. 2015 Feb;15(1):31-9. doi: 10.1007/s10238-014-0273-x. Epub 2014 Jan 29. Clin Exp Med. 2015. PMID: 24474501 Free article.