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OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance.
Pereira RO, Tadinada SM, Zasadny FM, Oliveira KJ, Pires KMP, Olvera A, Jeffers J, Souvenir R, Mcglauflin R, Seei A, Funari T, Sesaki H, Potthoff MJ, Adams CM, Anderson EJ, Abel ED. Pereira RO, et al. Among authors: seei a. EMBO J. 2017 Jul 14;36(14):2126-2145. doi: 10.15252/embj.201696179. Epub 2017 Jun 12. EMBO J. 2017. PMID: 28607005 Free PMC article.
Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling.
Riehle C, Weatherford ET, Wende AR, Jaishy BP, Seei AW, McCarty NS, Rech M, Shi Q, Reddy GR, Kutschke WJ, Oliveira K, Pires KM, Anderson JC, Diakos NA, Weiss RM, White MF, Drakos SG, Xiang YK, Abel ED. Riehle C, et al. Among authors: seei aw. JCI Insight. 2020 Mar 26;5(6):e134920. doi: 10.1172/jci.insight.134920. JCI Insight. 2020. PMID: 32213702 Free PMC article.