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Single-molecule analysis of ligand efficacy in β2AR-G-protein activation.
Gregorio GG, Masureel M, Hilger D, Terry DS, Juette M, Zhao H, Zhou Z, Perez-Aguilar JM, Hauge M, Mathiasen S, Javitch JA, Weinstein H, Kobilka BK, Blanchard SC. Gregorio GG, et al. Among authors: hauge m. Nature. 2017 Jul 6;547(7661):68-73. doi: 10.1038/nature22354. Epub 2017 Jun 7. Nature. 2017. PMID: 28607487 Free PMC article.
GPR40 (FFAR1) - Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo.
Hauge M, Vestmar MA, Husted AS, Ekberg JP, Wright MJ, Di Salvo J, Weinglass AB, Engelstoft MS, Madsen AN, Lückmann M, Miller MW, Trujillo ME, Frimurer TM, Holst B, Howard AD, Schwartz TW. Hauge M, et al. Mol Metab. 2014 Oct 24;4(1):3-14. doi: 10.1016/j.molmet.2014.10.002. eCollection 2015 Jan. Mol Metab. 2014. PMID: 25685685 Free PMC article.
GPR119, a Major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Coacting in Synergy With FFA1 (GPR40).
Ekberg JH, Hauge M, Kristensen LV, Madsen AN, Engelstoft MS, Husted AS, Sichlau R, Egerod KL, Timshel P, Kowalski TJ, Gribble FM, Reiman F, Hansen HS, Howard AD, Holst B, Schwartz TW. Ekberg JH, et al. Among authors: hauge m. Endocrinology. 2016 Dec;157(12):4561-4569. doi: 10.1210/en.2016-1334. Epub 2016 Oct 25. Endocrinology. 2016. PMID: 27779915 Free PMC article.
Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population.
Vestmar MA, Andersson EA, Christensen CR, Hauge M, Glümer C, Linneberg A, Witte DR, Jørgensen ME, Christensen C, Brandslund I, Lauritzen T, Pedersen O, Holst B, Grarup N, Schwartz TW, Hansen T. Vestmar MA, et al. Among authors: hauge m. J Med Genet. 2016 Sep;53(9):616-23. doi: 10.1136/jmedgenet-2015-103728. Epub 2016 Apr 11. J Med Genet. 2016. PMID: 27068006
185 results