Javitch JA - Search Results

1

Single-molecule analysis of ligand efficacy in β₂AR-G-protein activation.

Gregorio GG, Masureel M, Hilger D, Terry DS, Juette M, Zhao H, Zhou Z, Perez-Aguilar JM, Hauge M, Mathiasen S, Javitch JA, Weinstein H, Kobilka BK, Blanchard SC. Gregorio GG, et al. Among authors: javitch ja. Nature. 2017 Jul 6;547(7661):68-73. doi: 10.1038/nature22354. Epub 2017 Jun 7. Nature. 2017. PMID: 28607487 Free PMC article.

2

Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice.

Fu D, Ballesteros JA, Weinstein H, Chen J, Javitch JA. Fu D, et al. Among authors: javitch ja. Biochemistry. 1996 Sep 3;35(35):11278-85. doi: 10.1021/bi960928x. Biochemistry. 1996. PMID: 8784181

3

A cluster of aromatic residues in the sixth membrane-spanning segment of the dopamine D2 receptor is accessible in the binding-site crevice.

Javitch JA, Ballesteros JA, Weinstein H, Chen J. Javitch JA, et al. Biochemistry. 1998 Jan 27;37(4):998-1006. doi: 10.1021/bi972241y. Biochemistry. 1998. PMID: 9454590

4

The fourth transmembrane segment of the dopamine D2 receptor: accessibility in the binding-site crevice and position in the transmembrane bundle.

Javitch JA, Shi L, Simpson MM, Chen J, Chiappa V, Visiers I, Weinstein H, Ballesteros JA. Javitch JA, et al. Biochemistry. 2000 Oct 10;39(40):12190-9. doi: 10.1021/bi001069m. Biochemistry. 2000. PMID: 11015197

5

Probing conformational changes in neurotransmitter transporters: a structural context.

Goldberg NR, Beuming T, Soyer OS, Goldstein RA, Weinstein H, Javitch JA. Goldberg NR, et al. Among authors: javitch ja. Eur J Pharmacol. 2003 Oct 31;479(1-3):3-12. doi: 10.1016/j.ejphar.2003.08.052. Eur J Pharmacol. 2003. PMID: 14612133 Review.

6

A pincer-like configuration of TM2 in the human dopamine transporter is responsible for indirect effects on cocaine binding.

Sen N, Shi L, Beuming T, Weinstein H, Javitch JA. Sen N, et al. Among authors: javitch ja. Neuropharmacology. 2005 Nov;49(6):780-90. doi: 10.1016/j.neuropharm.2005.08.014. Epub 2005 Oct 10. Neuropharmacology. 2005. PMID: 16216288

7

Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation.

Guo W, Shi L, Filizola M, Weinstein H, Javitch JA. Guo W, et al. Among authors: javitch ja. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17495-500. doi: 10.1073/pnas.0508950102. Epub 2005 Nov 21. Proc Natl Acad Sci U S A. 2005. PMID: 16301531 Free PMC article.

8

State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.

Quick M, Yano H, Goldberg NR, Duan L, Beuming T, Shi L, Weinstein H, Javitch JA. Quick M, et al. Among authors: javitch ja. J Biol Chem. 2006 Sep 8;281(36):26444-54. doi: 10.1074/jbc.M602438200. Epub 2006 Jun 23. J Biol Chem. 2006. PMID: 16798738 Free article.

9

Functional selectivity and classical concepts of quantitative pharmacology.

Urban JD, Clarke WP, von Zastrow M, Nichols DE, Kobilka B, Weinstein H, Javitch JA, Roth BL, Christopoulos A, Sexton PM, Miller KJ, Spedding M, Mailman RB. Urban JD, et al. Among authors: javitch ja. J Pharmacol Exp Ther. 2007 Jan;320(1):1-13. doi: 10.1124/jpet.106.104463. Epub 2006 Jun 27. J Pharmacol Exp Ther. 2007. PMID: 16803859 Review.

10

A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function.

Beuming T, Shi L, Javitch JA, Weinstein H. Beuming T, et al. Among authors: javitch ja. Mol Pharmacol. 2006 Nov;70(5):1630-42. doi: 10.1124/mol.106.026120. Epub 2006 Jul 31. Mol Pharmacol. 2006. PMID: 16880288

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