Ganser LR - Search Results

1

Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics.

Clay MC, Ganser LR, Merriman DK, Al-Hashimi HM. Clay MC, et al. Among authors: ganser lr. Nucleic Acids Res. 2017 Aug 21;45(14):e134. doi: 10.1093/nar/gkx525. Nucleic Acids Res. 2017. PMID: 28609788 Free PMC article.

2

Development and application of aromatic [(13)C, (1)H] SOFAST-HMQC NMR experiment for nucleic acids.

Sathyamoorthy B, Lee J, Kimsey I, Ganser LR, Al-Hashimi H. Sathyamoorthy B, et al. Among authors: ganser lr. J Biomol NMR. 2014 Nov;60(2-3):77-83. doi: 10.1007/s10858-014-9856-9. Epub 2014 Sep 4. J Biomol NMR. 2014. PMID: 25186910 Free PMC article.

3

An RNA tertiary switch by modifying how helices are tethered.

Ganser LR, Mustoe AM, Al-Hashimi HM. Ganser LR, et al. Genome Biol. 2014 Jul 30;15(7):425. doi: 10.1186/s13059-014-0425-z. Genome Biol. 2014. PMID: 25315677 Free PMC article.

4

HIV-1 leader RNA dimeric interface revealed by NMR.

Ganser LR, Al-Hashimi HM. Ganser LR, et al. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13263-13265. doi: 10.1073/pnas.1615789113. Epub 2016 Nov 11. Proc Natl Acad Sci U S A. 2016. PMID: 27837023 Free PMC article. No abstract available.

5

Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR.

Patwardhan NN, Ganser LR, Kapral GJ, Eubanks CS, Lee J, Sathyamoorthy B, Al-Hashimi HM, Hargrove AE. Patwardhan NN, et al. Among authors: ganser lr. Medchemcomm. 2017 May 1;8(5):1022-1036. doi: 10.1039/C6MD00729E. Epub 2017 Mar 15. Medchemcomm. 2017. PMID: 28798862 Free PMC article.

6

High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble.

Ganser LR, Lee J, Rangadurai A, Merriman DK, Kelly ML, Kansal AD, Sathyamoorthy B, Al-Hashimi HM. Ganser LR, et al. Nat Struct Mol Biol. 2018 May;25(5):425-434. doi: 10.1038/s41594-018-0062-4. Epub 2018 May 4. Nat Struct Mol Biol. 2018. PMID: 29728655 Free PMC article.

7

The roles of structural dynamics in the cellular functions of RNAs.

Ganser LR, Kelly ML, Herschlag D, Al-Hashimi HM. Ganser LR, et al. Nat Rev Mol Cell Biol. 2019 Aug;20(8):474-489. doi: 10.1038/s41580-019-0136-0. Nat Rev Mol Cell Biol. 2019. PMID: 31182864 Free PMC article. Review.

8

Demonstration that Small Molecules can Bind and Stabilize Low-abundance Short-lived RNA Excited Conformational States.

Ganser LR, Kelly ML, Patwardhan NN, Hargrove AE, Al-Hashimi HM. Ganser LR, et al. J Mol Biol. 2020 Feb 14;432(4):1297-1304. doi: 10.1016/j.jmb.2019.12.009. Epub 2019 Dec 18. J Mol Biol. 2020. PMID: 31863746 Free PMC article.

9

Probing RNA Conformational Equilibria within the Functional Cellular Context.

Ganser LR, Chu CC, Bogerd HP, Kelly ML, Cullen BR, Al-Hashimi HM. Ganser LR, et al. Cell Rep. 2020 Feb 25;30(8):2472-2480.e4. doi: 10.1016/j.celrep.2020.02.004. Cell Rep. 2020. PMID: 32101729 Free PMC article.

10

Publisher Correction: High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble.

Ganser LR, Lee J, Rangadurai A, Merriman DK, Kelly ML, Kansal AD, Sathyamoorthy B, Al-Hashimi HM. Ganser LR, et al. Nat Struct Mol Biol. 2020 Jun;27(6):604. doi: 10.1038/s41594-020-0434-4. Nat Struct Mol Biol. 2020. PMID: 32376863

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