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Active-Site Tryptophan, the Target of Antineoplastic C-Terminal Binding Protein Inhibitors, Mediates Inhibitor Disruption of CtBP Oligomerization and Transcription Coregulatory Activities.
Dcona MM, Damle PK, Zarate-Perez F, Morris BL, Nawaz Z, Dennis MJ, Deng X, Korwar S, Singh SJ, Ellis KC, Royer WE, Bandyopadhyay D, Escalante C, Grossman SR. Dcona MM, et al. Among authors: zarate perez f. Mol Pharmacol. 2019 Jul;96(1):99-108. doi: 10.1124/mol.118.114363. Epub 2019 Apr 29. Mol Pharmacol. 2019. PMID: 31036695 Free PMC article.
The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Santosh V, Musayev FN, Jaiswal R, Zárate-Pérez F, Vandewinkel B, Dierckx C, Endicott M, Sharifi K, Dryden K, Henckaerts E, Escalante CR. Santosh V, et al. Among authors: zarate perez f. Nucleic Acids Res. 2020 Dec 16;48(22):12983-12999. doi: 10.1093/nar/gkaa1133. Nucleic Acids Res. 2020. PMID: 33270897 Free PMC article.
18 results